| 1 |
34624510 | Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects. | 2022 Feb |
1 |
| 2 |
34775061 | Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer. | 2022 Feb |
1 |
| 3 |
35044379 | A self-amplified ROS-responsive chemodrug-inhibitor conjugate for multi-drug resistance tumor therapy. | 2022 Feb 15 |
2 |
| 4 |
35075112 | Galectin-1 confers resistance to doxorubicin in hepatocellular carcinoma cells through modulation of P-glycoprotein expression. | 2022 Jan 24 |
2 |
| 5 |
35103340 | Approaches to minimize the effects of P-glycoprotein in drug transport: A review. | 2022 Feb 1 |
1 |
| 6 |
35215316 | PfMDR1 Transport Rates Assessed in Intact Isolated Plasmodium falciparum Digestive Vacuoles Reflect Functional Drug Resistance Relationship with pfmdr1 Mutations. | 2022 Feb 7 |
1 |
| 7 |
35401832 | Combating multidrug resistance and metastasis of breast cancer by endoplasmic reticulum stress and cell-nucleus penetration enhanced immunochemotherapy. | 2022 |
1 |
| 8 |
35471238 | Down-regulation of ABCB1 by Collateral Sensitivity Drugs Reverses Multidrug Resistance and Up-regulates Enolase I. | 2022 Apr 26 |
1 |
| 9 |
35601326 | Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators. | 2022 May 17 |
2 |
| 10 |
35634783 | Structure-based alteration of tryptophan residues of the multidrug transporter CmABCB1 to assess substrate binding using fluorescence spectroscopy. | 2022 Jun |
1 |
| 11 |
32229058 | Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells. | 2021 Jun |
2 |
| 12 |
33159693 | Conformational changes in the nucleotide-binding domains of P-glycoprotein induced by ATP hydrolysis. | 2021 Mar |
2 |
| 13 |
33275773 | ABCB1/MDR1/P-gp employs an ATP-dependent twist-and-squeeze mechanism to export hydrophobic drugs. | 2021 Mar |
2 |
| 14 |
33350827 | Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs. | 2021 Jan 12 |
2 |
| 15 |
33547668 | Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)? | 2021 Mar |
6 |
| 16 |
33735724 | A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance. | 2021 May |
1 |
| 17 |
33792091 | The effects and mechanisms of aloe-emodin on reversing adriamycin-induced resistance of MCF-7/ADR cells. | 2021 Jul |
2 |
| 18 |
33901197 | Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein. | 2021 |
1 |
| 19 |
33965440 | Exploiting the metabolic energy demands of drug efflux pumps provides a strategy to overcome multidrug resistance in cancer. | 2021 Aug |
6 |
| 20 |
33967805 | Transport of Drugs and Endogenous Compounds Mediated by Human OCT1: Studies in Single- and Double-Transfected Cell Models. | 2021 |
3 |
| 21 |
34000577 | Curcumin reverses doxorubicin resistance in colon cancer cells at the metabolic level. | 2021 Jul 15 |
1 |
| 22 |
34011375 | Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP). | 2021 May 19 |
2 |
| 23 |
34084427 | Active participation of membrane lipids in inhibition of multidrug transporter P-glycoprotein. | 2021 Apr 9 |
1 |
| 24 |
34418731 | Evolutionary dynamics of cancer multidrug resistance in response to olaparib and photodynamic therapy. | 2021 Nov |
2 |
| 25 |
34533937 | Reversing Multidrug Resistance by Inducing Mitochondrial Dysfunction for Enhanced Chemo-Photodynamic Therapy in Tumor. | 2021 Sep 29 |
1 |
| 26 |
34907862 | Computational binding affinity and molecular dynamic characterization of annonaceous acetogenins at nucleotide binding domain (NBD) of multi-drug resistance ATP-binding cassette sub-family B member 1 (ABCB1). | 2021 Dec 15 |
2 |
| 27 |
31750987 | P-glycoprotein: a role in the export of amyloid-β in Alzheimer's disease? | 2020 Feb |
2 |
| 28 |
31917466 | Propafenone analogue with additional H-bond acceptor group shows increased inhibitory activity on P-glycoprotein. | 2020 Mar |
2 |
| 29 |
31941029 | Sitravatinib Sensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs. | 2020 Jan 13 |
1 |
| 30 |
31963614 | Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: an in Vitro and in Silico Study. | 2020 Jan 17 |
1 |
| 31 |
31982489 | SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells. | 2020 Mar |
3 |
| 32 |
31991669 | Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells. | 2020 Jan 24 |
4 |
| 33 |
32014648 | Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update. | 2020 Mar |
2 |
| 34 |
32044354 | Biological evaluation of non-basic chalcone CYB-2 as a dual ABCG2/ABCB1 inhibitor. | 2020 May |
1 |
| 35 |
32054924 | Conversion of chemical to mechanical energy by the nucleotide binding domains of ABCB1. | 2020 Feb 13 |
1 |
| 36 |
32061772 | Canagliflozin inhibits p-gp function and early autophagy and improves the sensitivity to the antitumor effect of doxorubicin. | 2020 May |
1 |
| 37 |
32061787 | A dual PI3 kinase/mTOR inhibitor BEZ235 reverses doxorubicin resistance in ABCB1 overexpressing ovarian and pancreatic cancer cell lines. | 2020 Jun |
1 |
| 38 |
32064159 | MY-5445, a phosphodiesterase type 5 inhibitor, resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to cytotoxic anticancer drugs. | 2020 |
1 |
| 39 |
32092870 | Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells. | 2020 Feb 19 |
1 |
| 40 |
32111736 | In vivo FRET analyses reveal a role of ATP hydrolysis-associated conformational changes in human P-glycoprotein. | 2020 Apr 10 |
8 |
| 41 |
32148543 | Pulchinenosides from Pulsatilla Chinensis Increase P-Glycoprotein Activity and Induce P-Glycoprotein Expression. | 2020 |
1 |
| 42 |
32166458 | PD-L1 monoclonal antibody-decorated nanoliposomes loaded with Paclitaxel and P-gp transport inhibitor for the synergistic chemotherapy against multidrug resistant gastric cancers. | 2020 Mar 12 |
2 |
| 43 |
32232949 | Active transport of rhodamine 123 by the human multidrug transporter P-glycoprotein involves two independent outer gates. | 2020 Apr |
1 |
| 44 |
32260260 | Organosilicon Compounds, SILA-409 and SILA-421, as Doxorubicin Resistance-Reversing Agents in Human Colon Cancer Cells. | 2020 Apr 3 |
1 |
| 45 |
32268494 | Roles of Sorcin in Drug Resistance in Cancer: One Protein, Many Mechanisms, for a Novel Potential Anticancer Drug Target. | 2020 Apr 6 |
3 |
| 46 |
32331368 | Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death. | 2020 Apr 22 |
1 |
| 47 |
32422185 | Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter. | 2020 Aug 15 |
1 |
| 48 |
32706272 | A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer. | 2020 Dec |
1 |
| 49 |
32816867 | The Effects of Traditional Chinese Medicine on P-Glycoprotein-Mediated Multidrug Resistance and Approaches for Studying the Herb-P-Glycoprotein Interactions. | 2020 Oct |
2 |
| 50 |
32945146 | Engineering of a Core-Shell Nanoplatform to Overcome Multidrug Resistance via ATP Deprivation. | 2020 Oct |
2 |