Title : Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer.

Pub. Date : 2022 Feb

PMID : 34775061






1 Functional Relationships(s)
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1 The P-gp overexpression in cancer cells depends on several factors like adenosine triphosphate (ATP) hydrolysis, hypoxia-inducible factor 1 alpha (HIF-1alpha), and drug physicochemical properties such as lipophilicity, molecular weight, and molecular size. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens