Colchicine

carbonic anhydrase 4 ; Homo sapiens







23 Article(s)
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1 34986762 Recent Advances in Combretastatin A-4 Inspired Inhibitors of Tubulin Polymerization: An Update. 2022 2
2 33895499 Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines. 2021 Aug 5 1
3 34585392 Redox-responsive glycosylated combretastatin A-4 derivative as novel tubulin polymerization inhibitor for glioma and drug delivery. 2021 Nov 2
4 32325332 Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker. 2020 Jun 1
5 31059248 Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization. 2019 Jun 13 1
6 31674147 Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization. 2019 Dec 17 1
7 29432949 Synthesis and biological evaluation of carbamates derived from aminocombretastatin A-4 as vascular disrupting agents. 2018 Mar 10 1
8 30230828 Synthesis and in Vitro Bioactivity of Polyunsaturated Fatty Acid Conjugates of Combretastatin A-4. 2018 Sep 28 2
9 30429970 Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents. 2018 Oct 1 2
10 28034647 Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers. 2017 Feb 1 2
11 26899186 Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site. 2016 1
12 27138035 Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents. 2016 May 3 2
13 27515320 Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability. 2016 Sep 15 1
14 25461319 3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation. 2015 Jan 27 1
15 25529737 Microwave-assisted synthesis and biological evaluation of 3,4-diaryl maleic anhydride/N-substituted maleimide derivatives as combretastatin A-4 analogues. 2015 Feb 1 1
16 26061410 Synthesis and Biological Evaluation of 3-Alkyl-1,5-Diaryl-1H-Pyrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative Activity. 2015 1
17 23456551 TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis. 2013 Jul 2
18 23810282 Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity. 2013 Aug 15 1
19 23818224 Tubulin-interactive stilbene derivatives as anticancer agents. 2013 Sep 1
20 19837593 Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity. 2009 Nov 15 1
21 18074350 p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4. 2008 Apr 15 1
22 16183025 Structure-based discovery of a boronic acid bioisostere of combretastatin A-4. 2005 Sep 1
23 11058036 Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin. 2000 Oct 2