Genistein

tumor necrosis factor ; Homo sapiens







92 Article(s)
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1 33908440 Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway. 2021 May 21 1
2 34521933 Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations. 2021 Sep 14 1
3 30743203 Genistein suppresses psoriasis-related inflammation through a STAT3-NF-κB-dependent mechanism in keratinocytes. 2019 Apr 4
4 28923363 Anti-inflammatory effects of flavonoids in neurodegenerative disorders. 2018 Jun 10 1
5 29444128 Molecular action of isoflavone genistein in the human epithelial cell line HaCaT. 2018 1
6 30324111 Effect of Genistein and L-carnitine and Their Combination on Lipid Profile and Inflammatory Cytokines in Experimental Nephrotic Syndrome. 2018 Oct 1
7 29202800 Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway. 2017 Dec 4 1
8 27035424 Effects of resveratrol and genistein on nuclear factor‑κB, tumor necrosis factor‑α and matrix metalloproteinase‑9 in patients with chronic obstructive pulmonary disease. 2016 May 3
9 24666525 Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL. 2014 Mar 25 1
10 24669186 Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. 2014 5
11 25447760 Anti-inflammatory effect of gamma-irradiated genistein through inhibition of NF-κB and MAPK signaling pathway in lipopolysaccharide-induced macrophages. 2014 Dec 1
12 23587398 Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 mice. 2013 Oct 3 1
13 23764400 Suppression of T cell-induced osteoclast formation. 2013 Jul 12 1
14 23995107 Characterisation of apoptosis in myb-transformed hematopoietic cell (MTHC-A) lines: TNF-α-induced apoptosis and prevention by cAMP. 2013 1
15 24064732 Isoflavones derived from soy beans prevent MuRF1-mediated muscle atrophy in C2C12 myotubes through SIRT1 activation. 2013 1
16 21792602 Genistein inhibit cytokines or growth factor-induced proliferation and transformation phenotype in fibroblast-like synoviocytes of rheumatoid arthritis. 2012 Feb 5
17 22284780 Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. 2012 Jan 1
18 22494660 Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells. 2012 Apr 11 1
19 23109410 Genistein and daidzein, typical soy isoflavones, inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes. 2012 Dec 2
20 23221158 Tumor necrosis factor α stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells. 2012 1
21 21320636 Anti-inflammatory effect of genistein on non-alcoholic steatohepatitis rats induced by high fat diet and its potential mechanisms. 2011 Jun 1
22 21657246 In vitro evaluation of antioxidant and anti-inflammatory properties of genistein-modified hemodialysis membranes. 2011 Jul 11 1
23 22125674 Comparative effect of genistein and daidzein on the expression of MCP-1, eNOS, and cell adhesion molecules in TNF-α-stimulated HUVECs. 2011 Oct 1
24 19813266 Genistein induces receptor and mitochondrial pathways and increases apoptosis during BCL-2 knockdown in human malignant neuroblastoma SK-N-DZ cells. 2010 Mar 1
25 20067268 Genistein suppresses tumor necrosis factor-alpha-induced proliferation via the apoptotic signaling pathway in human aortic smooth muscle cells. 2010 Feb 10 4
26 20225658 The effects of genistein and puerarin on the activation of nuclear factor-kappaB and the production of tumor necrosis factor-alpha in asthma patients. 2010 Feb 6
27 20798528 Genistein suppression of TNF-alpha-induced fractalkine expression in endothelial cells. 2010 4
28 19082897 Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-alpha-induced apoptosis through the p38beta mitogen-activated protein kinase. 2009 Jan 3
29 19434061 Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts. 2009 Jul 1
30 18369347 Involvement of iNOS and NO in TNF-alpha-downregulated resistin gene expression in 3T3-L1 adipocytes. 2008 Jun 1
31 17251321 Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1. 2007 May 1
32 17404287 A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein. 2007 Apr 15 1
33 17934341 Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages. 2007 Aug 31 1
34 16420740 GM-CSF priming of human monocytes is dependent on ERK1/2 activation. 2006 1
35 16524734 Synthesis, cytotoxicity, and anti-inflammatory evaluation of 2-(furan-2-yl)-4-(phenoxy)quinoline derivatives. Part 4. 2006 Jul 1 1
36 16629226 The isoflavone genistein inhibits LPS-stimulated TNFalpha, but not IL-6 expression in monocytes from hemodialysis patients and healthy subjects. 2006 Apr 3
37 15779068 Effects of resveratrol, piceatannol, tri-acetoxystilbene, and genistein on the inflammatory response of human peripheral blood leukocytes. 2005 May 1
38 15805228 Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions. 2005 Aug 1
39 12547825 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. 2003 Apr 4 1
40 12645577 c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. 2003 Mar 14 1
41 12707358 Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression. 2003 May 1 1
42 14534369 Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-kappaB-dependent pathways in cultured human umbilical vein endothelial cells. 2003 Dec 2
43 12038621 Macrophage exposure to particulate titanium induces phosphorylation of the protein tyrosine kinase lyn and the phospholipases Cgamma-1 and Cgamma-2. 2002 May 2
44 12105943 Effects of anthocyanins and other phenolic compounds on the production of tumor necrosis factor alpha in LPS/IFN-gamma-activated RAW 264.7 macrophages. 2002 Jul 17 2
45 11305695 Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscle. 2001 Mar 1
46 11306564 Effects of the beta-amyloid and carboxyl-terminal fragment of Alzheimer's amyloid precursor protein on the production of the tumor necrosis factor-alpha and matrix metalloproteinase-9 by human monocytic THP-1. 2001 Jun 29 1
47 11368927 Soy isoflavone supplementation in healthy men prevents NF-kappa B activation by TNF-alpha in blood lymphocytes. 2001 Jun 1 1
48 11483407 Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway. 2001 Aug 1
49 10653605 Differential induction of tumor necrosis factor alpha and manganese superoxide dismutase by endotoxin in human monocytes: role of protein tyrosine kinase, mitogen-activated protein kinase, and nuclear factor kappaB. 2000 Mar 3
50 10880263 Regulation of interleukin 6 production in a human gastric epithelial cell line MKN-28. 2000 Jul 1