Title : Genistein suppresses tumor necrosis factor-alpha-induced proliferation via the apoptotic signaling pathway in human aortic smooth muscle cells.

Pub. Date : 2010 Feb 10

PMID : 20067268






4 Functional Relationships(s)
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1 Genistein suppresses tumor necrosis factor-alpha-induced proliferation via the apoptotic signaling pathway in human aortic smooth muscle cells. Genistein tumor necrosis factor Homo sapiens
2 The present study investigated the apoptotic effects of genistein on tumor necrosis factor-alpha (TNF-alpha)-induced proliferation in human aortic smooth muscle cells (HASMCs). Genistein tumor necrosis factor Homo sapiens
3 The present study investigated the apoptotic effects of genistein on tumor necrosis factor-alpha (TNF-alpha)-induced proliferation in human aortic smooth muscle cells (HASMCs). Genistein tumor necrosis factor Homo sapiens
4 In addition, genistein increased nucleosomal DNA fragmentation, increased the expression levels of Bax and c-Myc, and decreased the expression levels of Bcl-2 and Bcl-xL in TNF-alpha-induced HASMCs. Genistein tumor necrosis factor Homo sapiens