| 1 |
34850313 | Metformin effect in models of inflammation is associated with activation of ATP-dependent potassium channels and inhibition of tumor necrosis factor-α production. | 2022 Feb |
2 |
| 2 |
35605453 | Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients. | 2022 Jul |
1 |
| 3 |
32207597 | Study of the effect of metformin on expression levels of TNF-α and IL-18 in animal models of polycystic ovary syndrome. | 2021 Oct |
1 |
| 4 |
32828146 | Metformin repositioning in rheumatoid arthritis. | 2021 Jul-Aug |
2 |
| 5 |
33017649 | Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials. | 2021 Jan |
1 |
| 6 |
33141769 | Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids. | 2021 Apr 1 |
1 |
| 7 |
33444083 | Increased metformin dosage suppresses pro-inflammatory cytokine levels in systemic circulation and might contribute to its beneficial effects. | 2021 May 4 |
5 |
| 8 |
33517358 | Repurposing approved drugs for cancer therapy. | 2021 Mar 25 |
2 |
| 9 |
33580540 | Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity. | 2021 Jul |
1 |
| 10 |
33784336 | Profiling immuno-metabolic mediators of vitamin B12 deficiency among metformin-treated type 2 diabetic patients in Ghana. | 2021 |
1 |
| 11 |
33798839 | Effect of metformin on biomarkers of placental- mediated disease: A systematic review and meta-analysis. | 2021 Apr |
1 |
| 12 |
34277866 | Efficacy of Photobiomodulation and Metformin on Diabetic Cell Line of Human Periodontal Ligament Stem Cells through Keap1/Nrf2/Ho-1 Pathway. | 2021 Apr |
1 |
| 13 |
34284806 | Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism. | 2021 Jul 20 |
1 |
| 14 |
34611097 | Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids. | 2021 Oct 4 |
1 |
| 15 |
34670977 | Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids. | 2021 Oct 7 |
1 |
| 16 |
34717078 | Effect of metformin on adiponectin in PCOS: A meta-analysis and a systematic review. | 2021 Dec |
2 |
| 17 |
34763093 | Exploring metformin as a candidate drug for rosacea through network pharmacology and experimental validation. | 2021 Dec |
1 |
| 18 |
32194991 | Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis. | 2020 |
2 |
| 19 |
32452405 | Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia. | 2020 Jun |
1 |
| 20 |
32516360 | Acute Nicotine Treatment Alleviates LPS-Induced Impairment of Fear Memory Reconsolidation Through AMPK Activation and CRTC1 Upregulation in Hippocampus. | 2020 Dec 10 |
1 |
| 21 |
32518807 | Metformin, an AMPK Activator, Inhibits Activation of FLSs but Promotes HAPLN1 Secretion. | 2020 Jun 12 |
1 |
| 22 |
32607520 | Observational Study of Metformin and Risk of Mortality in Patients Hospitalized with Covid-19. | 2020 Jun 28 |
2 |
| 23 |
32646922 | Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial. | 2020 Sep 15 |
1 |
| 24 |
32769032 | Action of metformin therapy against advanced glycation, oxidative stress and inflammation in type 2 diabetes patients: 3 months follow-up study. | 2020 Sep - Oct |
1 |
| 25 |
32801814 | Association of TNF-α Gene Expression and Release in Response to Anti-Diabetic Drugs from Human Adipocytes in vitro. | 2020 |
1 |
| 26 |
32967076 | Systemic Oxidative Stress and Visceral Adipose Tissue Mediators of NLRP3 Inflammasome and Autophagy Are Reduced in Obese Type 2 Diabetic Patients Treated with Metformin. | 2020 Sep 21 |
1 |
| 27 |
30334569 | Metformin inhibits mTOR-HIF-1α axis and profibrogenic and inflammatory biomarkers in thioacetamide-induced hepatic tissue alterations. | 2019 Jun |
2 |
| 28 |
30520054 | Metformin inhibits pro-inflammatory responses via targeting nuclear factor-κB in HaCaT cells. | 2019 Jan |
2 |
| 29 |
30628691 | Protective effects of metformin on lipopolysaccharide‑induced airway epithelial cell injury via NF‑κB signaling inhibition. | 2019 Mar |
1 |
| 30 |
30753544 | Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects. | 2019 Jun 5 |
1 |
| 31 |
30890498 | [Efficacy and safety of metformin for Behcet's disease and its effect on Treg/Th17 balance: a single-blinded, before-after study]. | 2019 Feb 28 |
1 |
| 32 |
30959417 | The protective effect of silk fibroin on high glucose induced insulin resistance in HepG2 cells. | 2019 Jul |
2 |
| 33 |
31178745 | Metformin Monotherapy Downregulates Diabetes-Associated Inflammatory Status and Impacts on Mortality. | 2019 |
1 |
| 34 |
31326727 | Liraglutide in combination with metformin may improve the atherogenic lipid profile and decrease C-reactive protein level in statin treated obese patients with coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial. | 2019 Sep |
1 |
| 35 |
31442575 | Sitagliptin favorably modulates immune-relevant pathways in human beta cells. | 2019 Oct |
1 |
| 36 |
29148173 | Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation. | 2018 Jan |
1 |
| 37 |
29221717 | Effect of metformin combined with lifestyle modification versus lifestyle modification alone on proinflammatory-oxidative status in drug-naïve pre-diabetic and diabetic patients: A randomized controlled study. | 2018 May |
1 |
| 38 |
29383869 | Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. | 2018 Apr |
1 |
| 39 |
29466360 | Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia. | 2018 |
2 |
| 40 |
29513760 | Metformin suppresses retinal angiogenesis and inflammation in vitro and in vivo. | 2018 |
1 |
| 41 |
30097812 | Anti-inflammatory Action of Metformin with Respect to CX3CL1/CX3CR1 Signaling in Human Placental Circulation in Normal-Glucose Versus High-Glucose Environments. | 2018 Dec |
2 |
| 42 |
33385166 | Metformin: Possible Use of a Diabetes Drug in Treatment of Cancer. | 2018 |
1 |
| 43 |
28157701 | Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling. | 2017 Mar 28 |
1 |
| 44 |
28337819 | PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-β and TNF-α in mononuclear cells by insulin-sensitizing drugs. | 2017 Jul |
1 |
| 45 |
28410530 | Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK. | 2017 Jun |
1 |
| 46 |
28553078 | Effects of metformin extended release compared to immediate release formula on glycemic control and glycemic variability in patients with type 2 diabetes. | 2017 |
1 |
| 47 |
28699677 | Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP-9 expression but not direct TJ proteins expression regulation. | 2017 Dec |
1 |
| 48 |
29228440 | Metformin regulates tight junction of intestinal epithelial cells via MLCK-MLC signaling pathway. | 2017 Nov |
4 |
| 49 |
26305116 | Metformin inhibits proliferation and proinflammatory cytokines of human keratinocytes in vitro via mTOR-signaling pathway. | 2016 Jul |
1 |
| 50 |
26896068 | Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines. | 2016 Feb 19 |
1 |