Sphingomyelins

tumor necrosis factor ; Homo sapiens







73 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34608242 Differential lipids in pregnant women with subclinical hypothyroidism and their correlation to the pregnancy outcomes. 2021 Oct 4 4
2 29610685 Ceramide and Ischemia/Reperfusion Injury. 2018 1
3 21932365 Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α. 2012 Jan 3
4 21771974 The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models. 2011 Sep 1
5 22117546 Interaction of the nitric oxide signaling system with the sphingomyelin cycle and peroxidation on transmission of toxic signal of tumor necrosis factor-α in ischemia-reperfusion. 2011 Nov 1
6 17981627 Integration of cytokine biology and lipid metabolism in stroke. 2008 Jan 1 2
7 17573191 Inhibition of caspases but not of calpains temporarily protect against C2-ceramide-induced death of CAD cells. 2007 Jun 29 1
8 16183668 Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. 2006 Feb 1
9 16803890 Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production. 2006 Aug 25 1
10 15516208 A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria. 2005 Mar 15 1
11 15817701 TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx. 2005 Jul 1
12 15157676 Ceramide-induced enhancement of secretory phospholipase A2 expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells. 2004 Aug 1
13 12646059 Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum. 2003 Feb 11 1
14 14505946 Effect of Loxosceles gaucho venom on cell morphology and behaviour in vitro in the presence and absence of sphingomyelin. 2003 Sep 15 1
15 14563412 Saturated free fatty acid release and intracellular ceramide generation during apoptosis induction are closely related processes. 2003 Oct 20 2
16 14569872 [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. 2003 Jan-Feb 3
17 12154098 Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase. 2002 Oct 25 2
18 11404253 CTP:phosphocholine cytidylyltransferase inhibition by ceramide via PKC-alpha, p38 MAPK, cPLA2, and 5-lipoxygenase. 2001 Jul 1
19 11435466 Involvement of FAN in TNF-induced apoptosis. 2001 Jul 1
20 10666000 Tumor necrosis factor-alpha-mediated signal transduction in human neutrophils: involvement of sphingomyelin metabolites in the priming effect of TNF-alpha on the fMLP-stimulated superoxide production. 2000 3
21 10683565 Ceramide-induced sustained depression of synaptic currents mediated by ionotropic glutamate receptors in the hippocampus: an essential role of postsynaptic protein phosphatases. 2000 1
22 10788433 Divergence in regulation of nitric-oxide synthase and its cofactor tetrahydrobiopterin by tumor necrosis factor-alpha. Ceramide potentiates nitric oxide synthesis without affecting GTP cyclohydrolase I activity. 2000 May 5 1
23 10997557 Induction of tissue factor production but not the upregulation of adhesion molecule expression by ceramide in human vascular endothelial cells. 2000 Jul 1
24 11058554 Role of sphingosine in the tumor necrosis factor alpha stimulatory effect on lactate dehydrogenase A expression and activity in porcine Sertoli cells. 2000 Nov 3
25 11153078 HIV type 1 nef gene inhibits tumor necrosis factor alpha-induced apoptosis and promotes cell proliferation through the action of MAPK and JNK in human glial cells. 2000 Dec 10 1
26 10369458 Distinct effects of ceramide-generating pathways in prostate adenocarcinoma cells. 1999 May 1
27 10390188 Inhibition of human erythroid colony formation by ceramide. 1999 Jul 1
28 10567432 Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. 1999 Nov 26 2
29 10579257 Ceramide concentrations in septic patients: a possible marker of multiple organ dysfunction syndrome. 1999 Nov 1
30 9438415 Restoration of TNF-alpha-induced ceramide generation and apoptosis in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833. 1998 Jan 3
31 9466577 Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha. 1998 Feb 1
32 9478967 Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. 1998 Feb 27 1
33 9556624 Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death. 1998 May 1 1
34 9609949 [The role of sphingomyelin cycle products in development of apoptosis mediated by Fas receptors and tumor necrosis factor alpha]. 1998 Mar-Apr 1
35 9639567 The tumour necrosis factor-sensitive pool of sphingomyelin is resynthesized in a distinct compartment of the plasma membrane. 1998 Jul 1 1
36 9769704 Signaling in and regulation of ionizing radiation-induced apoptosis in endothelial cells. 1998 1
37 9030540 Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. 1997 Feb 21 1
38 9054379 Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-alpha-mediated cytotoxicity. 1997 Mar 14 3
39 9083023 1alpha,25-dihydroxyvitamin D3 induces sphingomyelin hydrolysis in HaCaT cells via tumor necrosis factor alpha. 1997 Apr 4 2
40 9110068 Interference of HIV-1 Nef in the sphingomyelin transduction pathway activated by tumour necrosis factor-alpha in human glial cells. 1997 Jan 2
41 8612652 Comparative study of the metabolic pools of sphingomyelin and phosphatidylcholine sensitive to tumor necrosis factor. 1996 Mar 1 3
42 8695867 Opposite effects of tumor necrosis factor alpha on the sphingomyelin-ceramide pathway in two myeloid leukemia cell lines: role of transverse sphingomyelin distribution in the plasma membrane. 1996 Aug 15 2
43 8702918 c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells. 1996 Aug 30 1
44 8726216 Sphingomyelinase inhibits in vitro Leydig cell function. 1996 May-Jun 2
45 8801194 Isolated guinea pig gastric chief cells express tumour necrosis factor receptors coupled with the sphingomyelin pathway. 1996 Feb 2
46 8830650 IgG immunoglobulins induce activation of the sphingomyelin cycle in HL-60 cells. 1996 Oct 7 6
47 8831497 Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells. 1996 Oct 1
48 8870666 Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes. 1996 Oct 1 1
49 8895358 Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. 1996 Nov 3
50 7477354 Phosphorylation of Raf by ceramide-activated protein kinase. 1995 Nov 16 2