Tyrosine

T cell receptor alpha variable 6-3 ; Mus musculus







49 Article(s)
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Pub. Year
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1 32434911 CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens. 2020 Jun 9 3
2 24470497 Relevance of Nck-CD3 epsilon interaction for T cell activation in vivo. 2014 Mar 1 1
3 22732588 Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function. 2012 Aug 1 1
4 21590764 TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections. 2011 Jul 1
5 20438120 Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. 2010 Jun 4 1
6 20847203 T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool. 2010 Dec 16 2
7 21030681 Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation. 2010 Nov 16 1
8 19290927 Abl tyrosine kinases in T-cell signaling. 2009 Mar 2
9 19682930 Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. 2009 Aug 21 1
10 17028588 RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development. 2006 Nov 2
11 15751964 Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor. 2005 Mar 15 6
12 15886116 Vav-family proteins in T-cell signalling. 2005 Jun 2
13 16259006 The CD3 gamma epsilon/delta epsilon signaling module provides normal T cell functions in the absence of the TCR zeta immunoreceptor tyrosine-based activation motifs. 2005 Dec 2
14 15470052 Linker for activation of T cells integrates positive and negative signaling in mast cells. 2004 Oct 15 1
15 12670394 Vav1: a key signal transducer downstream of the TCR. 2003 Apr 2
16 12682111 Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D. 2003 Apr 7 1
17 11828374 Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor. 2002 Feb 1
18 11970997 The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation. 2002 May 1 1
19 11157854 Conserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas. 2001 Feb 4
20 11457888 Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. 2001 Jul 16 2
21 11514605 T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase. 2001 Aug 20 3
22 10779742 Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). 2000 May 1 2
23 10903746 The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR. 2000 Aug 1 2
24 11005864 T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase. 2000 Sep 26 1
25 11069064 Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection. 2000 Oct 1
26 10593514 Thy-1/CD3 coengagement promotes TCR signaling and enhances particularly tyrosine phosphorylation of the raft molecule LAT. 1999 Aug 1
27 9557951 Signalling initiated with CD4-TCR or TCR-TCR interactions: comparison of tyrosine phosphorylation patterns and CD45 effects. 1998 Feb 3
28 9736612 Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. 1998 Sep 15 4
29 9794398 Differential requirements for ZAP-70 in TCR signaling and T cell development. 1998 Nov 1 1
30 9042429 CD4 dependence of activation threshold and TCR signalling in mouse T lymphocytes. 1997 Feb 4
31 9190928 Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70. 1997 Jun 15 5
32 9208839 A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. 1997 Jun 2
33 9294143 Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice. 1997 Sep 15 1
34 9354466 A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes. 1997 Oct 2
35 9366394 T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis. 1997 Nov 15 1
36 8647197 CD4-dependent and -independent association of protein tyrosine kinases to the T cell receptor/CD3 complex of CD4+ mouse T lymphocytes. 1996 Jun 2
37 8648096 Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes. 1996 Jun 15 1
38 8713105 Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. 1996 Jul 25 3
39 8906803 Impaired signaling in alloantigen-specific CD8+ T cells tolerized in vivo: employing a model of Ld-specific TCR transgenic mice transplanted with allogenic hearts under the cover of a short-term rapamycin treatment. 1996 Nov 15 1
40 9064344 Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. 1996 Sep 1 3
41 7589073 Carrier-reactive hapten-specific cytotoxic T lymphocyte clones originate from a highly preselected T cell repertoire: implications for chemical-induced self-reactivity. 1995 Oct 1
42 7621078 Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative. 1995 Jul 1
43 7512608 Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. 1994 Apr 15 1
44 7905417 T cell long-term hyporesponsiveness follows antigen receptor engagement and results from defective signal transduction. 1994 Feb 1
45 7929062 Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction. 1994 Sep 30 5
46 1375326 Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck. 1992 Jun 4
47 1706380 CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation. 1991 Mar 15 2
48 1697878 Tyrosine phosphorylation is an obligatory event in IL-2 secretion. 1990 Oct 1 1
49 2190221 Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. 1990 Jun 3