Glycyrrhizic Acid

high mobility group box 1 ; Homo sapiens







69 Article(s)
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1 34427852 Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway. 2022 Feb 1
2 34617194 Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma. 2022 May 1
3 35432719 Glycyrrhizin Attenuates Hypoxic-Ischemic Brain Damage by Inhibiting Ferroptosis and Neuroinflammation in Neonatal Rats via the HMGB1/GPX4 Pathway. 2022 6
4 32602358 Glycyrrhizin, an HMGB1 inhibitor, Suppresses Interleukin-1β-Induced Inflammatory Responses in Chondrocytes from Patients with Osteoarthritis. 2021 Dec 4
5 33107103 HMGB1 as a therapeutic target in disease. 2021 May 1
6 33347772 Effects of Glycyrrhizin Treatment on Diabetic Cornea. 2021 Jan-Feb 1
7 33611821 Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol. 2021 Aug 1
8 33773396 Glycyrrhizin prevents SARS-CoV-2 S1 and Orf3a induced high mobility group box 1 (HMGB1) release and inhibits viral replication. 2021 Jun 1
9 34289368 Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia. 2021 Jul 20 2
10 34684184 Targeting Inflammation Driven by HMGB1 in Bacterial Keratitis-A Review. 2021 Sep 25 2
11 34739475 HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19. 2021 Oct 1 2
12 34867338 Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting. 2021 2
13 34934826 Glycyrrhizin and its derivatives promote hepatic differentiation via sweet receptor, Wnt, and Notch signaling. 2021 Dec 2
14 31769590 Cigarette smoke-induced HMGB1 translocation and release contribute to migration and NF-κB activation through inducing autophagy in lung macrophages. 2020 Jan 1
15 31872339 Glycyrrhizin Prevents Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke with Delayed Thrombolysis Through Targeting Peroxynitrite-Mediated HMGB1 Signaling. 2020 Oct 5
16 31916113 Restoration of calcium-induced differentiation potential and tight junction formation in HaCaT keratinocytes by functional attenuation of overexpressed high mobility group box-1 protein. 2020 Feb 2
17 31924647 Neuroimmune/Hematopoietic Axis with Distinct Regulation by the High-Mobility Group Box 1 in Association with Tachykinin Peptides. 2020 Feb 15 2
18 32117622 Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells. 2020 6
19 32275943 HMGB1 release promotes paclitaxel resistance in castration-resistant prostate cancer cells via activating c-Myc expression. 2020 Aug 2
20 32340172 Glycyrrhizin Inhibits PEDV Infection and Proinflammatory Cytokine Secretion via the HMGB1/TLR4-MAPK p38 Pathway. 2020 Apr 23 2
21 32419317 TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury. 2020 Jun 1
22 32523355 Inhibition of HMGB1 Overcomes Resistance to Radiation and Chemotherapy in Nasopharyngeal Carcinoma. 2020 3
23 32623356 N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study. 2020 Oct 2
24 32633407 Glycyrrhizin improves inflammation and apoptosis via suppressing HMGB1 and PI3K/mTOR pathway in lipopolysaccharide-induced acute liver injury. 2020 Jun 1
25 32722545 The Complex Relationship between Diabetic Retinopathy and High-Mobility Group Box: A Review of Molecular Pathways and Therapeutic Strategies. 2020 Jul 26 1
26 32963505 Beneficial Effects of Glycyrrhizin in Chronic Periodontitis Through the Inhibition of Inflammatory Response. 2020 Jul-Sep 2
27 33287126 Role of HMGB1/TLR4 Axis in Ischemia/Reperfusion-Impaired Extracellular Glutamate Clearance in Primary Astrocytes. 2020 Dec 3 1
28 33313438 HMGB1 as a potential biomarker and therapeutic target for severe COVID-19. 2020 Dec 1
29 30634142 Glycyrrhizin attenuates hepatic ischemia-reperfusion injury by suppressing HMGB1-dependent GSDMD-mediated kupffer cells pyroptosis. 2019 Mar 2
30 30782274 [Expression of high-mobility group box 1 in neonates with sepsis]. 2019 Feb 2
31 30832473 Glycyrrhizin Attenuates the Process of Epithelial-to-Mesenchymal Transition by Modulating HMGB1 Initiated Novel Signaling Pathway in Prostate Cancer Cells. 2019 Mar 27 6
32 31105713 Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions. 2019 4
33 31190067 Polyamine-stimulation of arsenic-transformed keratinocytes. 2019 Aug 22 1
34 31336567 High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction. 2019 Jul 22 2
35 31450620 Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis. 2019 Aug 24 2
36 31497226 Glycyrrhizin suppresses inflammation and cell apoptosis by inhibition of HMGB1 via p38/p-JUK signaling pathway in attenuating intervertebral disc degeneration. 2019 7
37 31507379 Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation. 2019 1
38 31545873 Protective effect of glycyrrhizic acid on cerebral ischemia/reperfusion injury via inhibiting HMGB1-mediated TLR4/NF-κB pathway. 2019 Nov 3
39 29241031 The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways. 2018 Feb 2
40 29329282 Induction of high-mobility group Box-1 in vitro and in vivo by respiratory syncytial virus. 2018 May 4
41 29436639 Glycyrrhizin affects monocyte migration and apoptosis by blocking HMGB1 signaling. 2018 Apr 6
42 29448108 Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization. 2018 Feb 26 5
43 29568761 Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level. 2018 3
44 29676481 High-mobility group box 1 in Parkinson's disease: from pathogenesis to therapeutic approaches. 2018 Aug 1
45 29763588 Glycyrrhizin ameliorates inflammatory pain by inhibiting microglial activation-mediated inflammatory response via blockage of the HMGB1-TLR4-NF-kB pathway. 2018 Aug 1 2
46 29795370 HMGB1 released from intestinal epithelia damaged by cholera toxin adjuvant contributes to activation of mucosal dendritic cells and induction of intestinal cytotoxic T lymphocytes and IgA. 2018 May 24 2
47 30061484 Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures. 2018 Jul 30 2
48 30119194 The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice. 2018 Oct 3
49 30325653 Glycyrrhizin, a Potential Drug for Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1. 2018 Dec 3
50 30587909 Efficacy and safety of glycyrrhizin 2.5% eye drops in the treatment of moderate dry eye disease: results from a prospective, open-label pilot study. 2018 1