Pub. Date : 2020 Jul-Sep
PMID : 32963505
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | TNF-alpha-treated human periodontal ligament stem cell (hPDLSC) model was established, and was administrated with 1, 2 or 5 mM glycyrrhizin for 24 h. After treatment, the expression of HMGB1and inflammatory cytokines was monitored. | Glycyrrhizic Acid | high mobility group box 1 | Homo sapiens |
2 | Glycyrrhizin significantly prevented TNF-alpha-induced expression of HMGB1 (691.5 +- 136.4 vs 142.8 +- 57.3 pg/mL), IL-6 (388.1 +- 85.2 vs 189.4 +- 61.2 pg/mL) and IL-1beta (176.3 +- 47.2 vs 53.9 +- 25.7 pg/mL) in hPDLSC. | Glycyrrhizic Acid | high mobility group box 1 | Homo sapiens |