Fingolimod Hydrochloride

sphingosine-1-phosphate receptor 1 ; Homo sapiens







31 Article(s)
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1 35158767 Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters. 2022 Jan 19 1
2 33603656 The Therapeutic Targets of Fingolimod (FTY720) Are Involved in Pathological Processes in the Frontal Cortex of Alzheimer's Disease Patients: A Network Pharmacology Study. 2021 2
3 33797705 Sphingosine 1-Phosphate Receptor Modulators for Multiple Sclerosis. 2021 Apr 3
4 33010954 Targeting the Sphingosine-1-Phosphate Axis for Developing Non-narcotic Pain Therapeutics. 2020 Nov 6
5 30785748 Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials. 2019 Mar 14 1
6 30828332 Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells. 2019 3
7 31526917 Impact of fingolimod on CD4+ T cell subset and cytokine profile of relapsing remitting multiple sclerosis patients. 2019 Dec 15 2
8 30083262 Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine. 2018 1
9 28356890 Evaluation and Optimization of in silico designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis. 2017 Mar 2
10 28716816 Sphingosine-1-Phosphate Receptor-1 Promotes Environment-Mediated and Acquired Chemoresistance. 2017 Nov 1
11 27055778 Fingolimod therapy modulates circulating B cell composition, increases B regulatory subsets and production of IL-10 and TGFβ in patients with Multiple Sclerosis. 2016 Jun 1
12 27663260 To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. 2016 Nov 2
13 25582213 Therapeutic interference with leukocyte recirculation in multiple sclerosis. 2015 Mar 2
14 26130058 Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound. 2015 Nov 2
15 26648781 Influence of fingolimod on basic lymphocyte subsets frequencies in the peripheral blood of multiple sclerosis patients - preliminary study. 2015 1
16 24239768 Second generation S1P pathway modulators: research strategies and clinical developments. 2014 May 1
17 25239520 Prominence of central sphingosine-1-phosphate receptor-1 in attenuating aβ-induced injury by fingolimod. 2014 Dec 3
18 25518386 [Fingolimod treatment in multiple sclerosis]. 2014 Nov 1
19 23518370 Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy. 2013 May 15 1
20 24069553 Sphingosine-1-phosphate: Driver of NFκB and STAT3 persistent activation in chronic intestinal inflammation and colitis-associated cancer. 2013 Jul 1 1
21 22493799 [Research progress of the selective sphingosine-1-phosphate receptor 1 agonists]. 2012 Jan 2
22 22999882 A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis. 2012 Sep 21 2
23 21464424 Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS. 2011 Apr 5 1
24 21710707 [Current treatment of multiple sclerosis]. 2011 Feb 1
25 24900328 Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate. 2011 Jun 9 1
26 20413685 Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. 2010 Jun 1
27 19814729 FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system. 2009 Nov 1
28 18474015 Recent trials for FTY720 (fingolimod): a new generation of immunomodulators structurally similar to sphingosine. 2008 Jan 4
29 16365393 Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection. 2006 Jan 1 1
30 16393960 Lymphoid sequestration of alloreactive memory CD4 T cells promotes cardiac allograft survival. 2006 Jan 15 1
31 16549044 Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. 2006 Feb 1