Title : Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS.

Pub. Date : 2011 Apr 5

PMID : 21464424






1 Functional Relationships(s)
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1 Fingolimod is a functional antagonist of the sphingosine-1-phosphate receptor 1 and thereby inhibits sphingosine-1-phosphate-dependent lymphocyte egress from secondary lymphoid tissues, resulting in a pronounced lymphopenia in the peripheral blood. Fingolimod Hydrochloride sphingosine-1-phosphate receptor 1 Homo sapiens