Title : The Therapeutic Targets of Fingolimod (FTY720) Are Involved in Pathological Processes in the Frontal Cortex of Alzheimer's Disease Patients: A Network Pharmacology Study.

Pub. Date : 2021

PMID : 33603656






2 Functional Relationships(s)
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1 Background: The sphingosine-1-phosphate receptor (S1PR) modulator fingolimod (FTY720), which is commonly used as an immunomodulator in multiple sclerosis treatment, has recently been found to reduce pathological changes in the brain tissue of Alzheimer"s disease (AD) animal models, but this has yet to be verified in human brain tissue. Fingolimod Hydrochloride sphingosine-1-phosphate receptor 1 Homo sapiens
2 Background: The sphingosine-1-phosphate receptor (S1PR) modulator fingolimod (FTY720), which is commonly used as an immunomodulator in multiple sclerosis treatment, has recently been found to reduce pathological changes in the brain tissue of Alzheimer"s disease (AD) animal models, but this has yet to be verified in human brain tissue. Fingolimod Hydrochloride sphingosine-1-phosphate receptor 1 Homo sapiens