benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

tumor necrosis factor ; Mus musculus







36 Article(s)
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1 32460187 Triad3A displays a critical role in suppression of cerebral ischemic/reperfusion (I/R) injury by regulating necroptosis. 2020 Aug 1
2 28770700 Detection of Necroptosis in Ligand-Mediated and Hypoxia-Induced Injury of Hepatocytes Using a Novel Optic Probe-Detecting Receptor-Interacting Protein (RIP)1/RIP3 Binding. 2018 Apr 10 2
3 29337003 Mouse lung fibroblasts are highly susceptible to necroptosis in a reactive oxygen species-dependent manner. 2018 Jul 2
4 29664014 RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. 2018 May 1 1
5 29170425 TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3. 2017 Nov 23 2
6 27605011 Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-κB. 2016 Oct 15 1
7 27616656 Caspase Inhibition Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro. 2016 Oct 2
8 25398540 RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells. 2015 Jan 1
9 25898986 PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo. 2015 Aug 1
10 24577082 Akt and mTOR mediate programmed necrosis in neurons. 2014 Feb 27 1
11 24751948 Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells. 2014 5
12 23941769 Negatively-regulated necroptosis by autophagy required caspase-6 activation in TNFα-treated murine fibrosarcoma L929 cells. 2013 Nov 4
13 22371307 Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-α-induced shock. 2012 May 9 2
14 23000518 RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy. 2012 Dec 2
15 20539307 zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway. 2011 Jan 5
16 22027097 TNFα-induced necroptosis and autophagy via supression of the p38-NF-κB survival pathway in L929 cells. 2011 3
17 20702393 NF-kappaB regulates the expression of Nucling, a novel apoptosis regulator, with involvement of proteasome and caspase for its degradation. 2010 Nov 1
18 18931327 The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling. 2009 Apr 1
19 18191813 Release of arachidonic acid induced by tumor necrosis factor-alpha in the presence of caspase inhibition: evidence for a cytosolic phospholipase A2alpha-independent pathway. 2008 Mar 15 2
20 17206708 Remission-inducing effect of anti-TNF monoclonal antibody in TNBS colitis: mechanisms beyond neutralization? 2007 Mar 1
21 16420519 Differential caspase-9-dependent signaling pathway between tumor necrosis factor receptor- and Fas-mediated hepatocyte apoptosis in mice. 2006 Feb 1
22 16537794 Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-rich atherosclerotic plaques. 2006 Jun 1
23 16874073 z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization. 2006 Oct-Dec 1
24 16418768 The augmentation of TNFalpha-induced cell death in murine L929 fibrosarcoma by the pan-caspase inhibitor Z-VAD-fmk through pre-mitochondrial and MAPK-dependent pathways. 2005 Dec 4
25 16418769 A comparison of the signal pathways between the TNF alpha- and oridonin-induced murine L929 fibrosarcoma cell death. 2005 Dec 1
26 12652297 Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2. 2003 Apr 1
27 12126645 Activation of platelet caspases by TNF and its consequences for kinetics. 2002 May 21 1
28 11361017 FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4. 2001 Jan 1 1
29 10827087 Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression. 2000 Aug 11 3
30 10988295 Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells. 2000 Dec 1 1
31 10212002 TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk. 1999 Apr 1
32 10373464 Bcl-2 and caspase inhibition cooperate to inhibit tumor necrosis factor-alpha-induced cell death in a Bcl-2 cleavage-independent fashion. 1999 Jun 25 2
33 10425195 Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage. 1999 Aug 2 1
34 10455154 Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species. 1999 Aug 27 1
35 10534346 Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation. 1999 Nov 1
36 9565639 Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. 1998 May 4 3