Pub. Date : 1998 May 4
PMID : 9565639
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | zVAD-fmk and zD-fmk, two broad-spectrum inhibitors of caspases, also rendered the cells more sensitive, since the half-maximal dose for TNF-mediated necrosis decreased by a factor of 1,000. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | tumor necrosis factor | Mus musculus |
| 2 | The presence of zVAD-fmk also resulted in a more rapid increase of TNF-mediated production of oxygen radicals. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | tumor necrosis factor | Mus musculus |
| 3 | zVAD-fmk-dependent sensitization of TNF cytotoxicity could be completely inhibited by the oxygen radical scavenger butylated hydroxyanisole. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | tumor necrosis factor | Mus musculus |