tanespimycin

epidermal growth factor receptor ; Homo sapiens







12 Article(s)
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Pub. Year
#Total Relationships
1 33537004 Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing's Disease. 2020 1
2 28542269 The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells. 2017 1
3 25115740 Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models. 2014 Dec 1
4 23507703 PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer. 2013 Jun 1
5 23003202 Lapatinib and 17AAG reduce 89Zr-trastuzumab-F(ab')2 uptake in SKBR3 tumor xenografts. 2012 Nov 5 2
6 20940188 Activity of IPI-504, a novel heat-shock protein 90 inhibitor, in patients with molecularly defined non-small-cell lung cancer. 2010 Nov 20 1
7 18199556 Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel. 2008 Jan 15 1
8 18303439 Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway. 2008 Feb 1
9 18769157 Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition. 2008 Sep 15 1
10 16731752 Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT. 2006 May 4
11 16367912 Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis. 2005 Dec 1
12 11156083 Modulation of metastasis phenotypes of non-small cell lung cancer cells by 17-allylamino 17-demethoxy geldanamycin. 2000 Dec 2