Oligonucleotides

epidermal growth factor receptor ; Homo sapiens







64 Article(s)
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1 34064412 Composites of Nucleic Acids and Boron Clusters (C2B10H12) as Functional Nanoparticles for Downregulation of EGFR Oncogene in Cancer Cells. 2021 May 4 1
2 31925985 ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target. 2020 Mar 2
3 31164704 Sensitive detection of low-abundance in-frame deletions in EGFR exon 19 using novel wild-type blockers in real-time PCR. 2019 Jun 4 1
4 29514240 Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides. 2018 Apr 20 1
5 29748615 Specific targeting of point mutations in EGFR L858R-positive lung cancer by CRISPR/Cas9. 2018 Jul 1
6 28272528 EGFR induces DNA decomposition via phosphodiester bond cleavage. 2017 Mar 8 1
7 28425453 Aptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers. 2017 Apr 20 1
8 28832537 High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents. 2017 Aug 23 2
9 28881435 Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case. 2017 Nov 21 2
10 23103856 Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling. 2013 Jan 1
11 23395887 Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. 2013 Apr 1
12 23534780 EGFR antisense oligonucleotides encapsulated with nanoparticles decrease EGFR, MAPK1 and STAT5 expression in a human colon cancer cell line. 2013 3
13 23571736 Toll-like receptor 9 agonist IMO cooperates with everolimus in renal cell carcinoma by interfering with tumour growth and angiogenesis. 2013 Apr 30 2
14 23953842 Epidermal growth factor receptor targeting in cancer: a review of trends and strategies. 2013 Nov 1
15 21573974 Differentiated prostatic antigen expression in LNCaP cells following treatment with bispecific antisense oligonucleotides directed against BCL-2 and EGFR. 2012 Jun 1
16 21325655 Biotinylated probe isolation of targeted gene region improves detection of T790M epidermal growth factor receptor mutation via peptide nucleic acid-enriched real-time PCR. 2011 May 1
17 21756831 [Comparison of real-time quantitative PCR and allele-specific oligonucleotide PCR for detections of L858R mutation in epidermal growth factor receptor gene exon 21]. 2011 May 1
18 21890455 Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers. 2011 Oct 15 2
19 22321542 [Epidermal growth factor receptor gene mutations and clinicopathologic correlation in 309 patients with non-small cell lung cancer]. 2011 Oct 2
20 19937163 Increased prostate-specific membrane antigen expression in LNCaP cells following treatment with bispecific antisense oligonucleotides directed against bcl-2 and EGFR. 2010 Dec 1
21 19347870 Down-regulation of epidermal growth factor receptor induced by estrogens and phytoestrogens promotes the differentiation of U2OS human osteosarcoma cells. 2009 Jul 1
22 19766894 Epidermal growth factor promotes epidermal growth factor receptor nuclear accumulation by a pathway dependent on cytoskeleton integrity in human breast cancer cells. 2009 Jul 1
23 19836242 An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis. 2009 Nov 17 1
24 19903791 A novel toll-like receptor 9 agonist cooperates with trastuzumab in trastuzumab-resistant breast tumors through multiple mechanisms of action. 2009 Nov 15 3
25 17972023 Treatment of MCF-7 breast cancer cells employing mono- and bispecific antisense oligonucleotides having binding specificity toward proteins associated with autocrine regulated growth and BCL-2. 2008 3
26 18025070 Antitumor mechanisms of systemically administered epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck. 2008 Mar 7
27 18207161 Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding affibody molecule. 2008 Mar 7 1
28 17636117 TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts. 2007 Jul 24 3
29 17848743 Bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and bcl-2 for the treatment of prostate tumors. 2007 3
30 17917084 Combination chemotherapy employing bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and bcl-2 for the treatment of prostate tumors. 2007 2
31 17922545 Oligonucleotide-coated metallic nanoparticles as a flexible platform for molecular imaging agents. 2007 Nov-Dec 1
32 16597093 Targeting the epidermal growth factor receptor (EGFR)--a new therapeutic option in oncology? 2006 Jan 7 1
33 16870352 Synthesis of branched antisense oligonucleotides having multiple specificities. Treatment of hormone insensitive prostate cancer. 2006 4
34 17136230 Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy. 2006 Oct 4
35 15720189 Chemosensitization by antisense oligonucleotides targeting MDM2. 2005 Feb 2
36 16075456 Analysis of the epidermal growth factor receptor specific transcriptome: effect of receptor expression level and an activating mutation. 2005 Oct 1 1
37 14688027 Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R). 2004 Apr 1
38 15599851 The epidermal growth factor receptor signaling network in head and neck carcinogenesis and implications for targeted therapy. 2004 Dec 2
39 12665682 Inhibition of PC-3 prostate cancer cell growth in vitro using both antisense oligonucleotides and taxol. 2003 4
40 12948863 Messenger RNA expression profiling of genes involved in epidermal growth factor receptor signalling in human cancer cells treated with scanning array-designed antisense oligonucleotides. 2003 Sep 1 1
41 14763145 [Therapeutic implications of epidermal growth factor receptor in lung cancer]. 2003 Nov 1
42 11830539 Early Growth Response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia. 2002 Feb 1 2
43 12063543 EGFR antisense treatment of human HNSCC cell lines down-regulates VEGF expression and endothelial cell migration. 2002 Jul 2
44 12119273 Protein kinase A as target for novel integrated strategies of cancer therapy. 2002 Jun 1
45 12616956 Backbone modification alters the efficacy of antisense oligonucleotides directed against mRNA encoding either TGF-alpha or EGFR in the treatment of prostate cancer cell lines. 2002 Dec 3
46 11278982 c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation. 2001 May 11 3
47 11410862 Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis, and cooperate with cytotoxic drugs in human cancer cell lines. 2001 Jul 15 8
48 11484948 The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy. 2001 Jun 1
49 11778757 Treatment of the T98G glioblastoma cell line with antisense oligonucleotides directed toward mRNA encoding transforming growth factor-alpha and the epidermal growth factor receptor. 2001 5
50 10206071 Antisense oligonucleotides to the epidermal growth factor receptor. 1999 Jan 5