Title : Aptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.

Pub. Date : 2017 Apr 20

PMID : 28425453






1 Functional Relationships(s)
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1 Overall, we demonstrate a novel mechanism of action for CL4 related with integrin alphavbeta3-EGFR interaction, that may help to develop new oligonucleotide-based strategy addressing unmet need for TNBCs therapy. Oligonucleotides epidermal growth factor receptor Homo sapiens