Title : ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target.

Pub. Date : 2020 Mar

PMID : 31925985






2 Functional Relationships(s)
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Protein Name
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1 An anti-sense oligonucleotide (ASO) against ARL4C (ARL4C ASO-1316) inhibited RAS-related C3 botulinum toxin substrate activity and nuclear import of Yes-associated protein and transcriptional coactivator with PDZ-binding motif, and suppressed in vitro proliferation and migration of lung cancer cells with KRAS or epidermal growth factor receptor (EGFR) mutations. Oligonucleotides epidermal growth factor receptor Homo sapiens
2 An anti-sense oligonucleotide (ASO) against ARL4C (ARL4C ASO-1316) inhibited RAS-related C3 botulinum toxin substrate activity and nuclear import of Yes-associated protein and transcriptional coactivator with PDZ-binding motif, and suppressed in vitro proliferation and migration of lung cancer cells with KRAS or epidermal growth factor receptor (EGFR) mutations. Oligonucleotides epidermal growth factor receptor Homo sapiens