| 1 |
34315388 | New C2- and N3-Modified Thieno[2,3-d]Pyrimidine Conjugates with Cytotoxicity in the Nanomolar Range. | 2022 |
1 |
| 2 |
35297084 | An appraisal of anticancer activity with structure-activity relationship of quinazoline and quinazolinone analogues through EGFR and VEGFR inhibition: A review. | 2022 Mar 16 |
4 |
| 3 |
35364239 | Synthesis and biological evaluation of new series of quinazoline derivatives as EGFR/HER2 dual-target inhibitors. | 2022 Jul 1 |
2 |
| 4 |
35607598 | Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights. | 2022 |
1 |
| 5 |
35633554 | Identification of oxazolo[4,5-g]quinazolin-2(1H)-one Derivatives as EGFR Inhibitors for Cancer Prevention. | 2022 May 1 |
1 |
| 6 |
32236267 | Novel anilino quinazoline-based EGFR tyrosine kinase inhibitors for treatment of non-small cell lung cancer. | 2021 Jan 21 |
1 |
| 7 |
32593282 | Bestowal of Quinazoline Scaffold in Anticancer Drug Discovery. | 2021 |
2 |
| 8 |
33647840 | Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer. | 2021 Apr 1 |
1 |
| 9 |
33685233 | Design, synthesis, biological evaluation and docking study of novel quinazoline derivatives as EGFR-TK inhibitors. | 2021 Apr |
2 |
| 10 |
33760108 | A novel anthraquinone‑quinazoline hybrid 7B blocks breast cancer metastasis and EMT via targeting EGFR and Rac1. | 2021 May |
3 |
| 11 |
34028091 | Evaluation of anti-EGFR potential of quinazoline derivatives using molecular docking: An in silico approach. | 2021 May 24 |
3 |
| 12 |
34192644 | Design, synthesis and biological evaluation of novel 2,4-disubstituted quinazoline derivatives targeting H1975 cells via EGFR-PI3K signaling pathway. | 2021 Aug 1 |
1 |
| 13 |
34338597 | Identification of the structural features of quinazoline derivatives as EGFR inhibitors using 3D-QSAR modeling, molecular docking, molecular dynamics simulations and free energy calculations. | 2021 Aug 2 |
2 |
| 14 |
34399322 | Novel, selective acrylamide linked quinazolines for the treatment of double mutant EGFR-L858R/T790M Non-Small-Cell lung cancer (NSCLC). | 2021 Oct |
2 |
| 15 |
34655841 | Design, synthesis and biological evaluation of cinnamamide-quinazoline derivatives as potential EGFR inhibitors to reverse T790M mutation. | 2021 Dec |
2 |
| 16 |
31838290 | Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2. | 2020 Jan |
1 |
| 17 |
32139324 | Design and synthesis of a novel class EGFR/HER2 dual inhibitors containing tricyclic oxazine fused quinazolines scaffold. | 2020 May 1 |
2 |
| 18 |
32145644 | Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules. | 2020 Apr 15 |
1 |
| 19 |
32171987 | Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents. | 2020 May |
1 |
| 20 |
32397330 | Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors. | 2020 May 8 |
1 |
| 21 |
32527559 | Discovery of quinoline-based irreversible BTK inhibitors. | 2020 Jul 15 |
1 |
| 22 |
32603111 | Mechanistic Study of Potent Fluorinated EGFR Kinase Inhibitors with a Quinazoline Scaffold against L858R/T790M/C797S Resistance Mutation: Unveiling the Fluorine Substituent Cooperativity Effect on the Inhibitory Activity. | 2020 Jul 16 |
1 |
| 23 |
32619886 | Design, synthesis and biological evaluation of 4-aniline quinazoline derivatives conjugated with hydrogen sulfide (H2S) donors as potent EGFR inhibitors against L858R resistance mutation. | 2020 Sep 15 |
1 |
| 24 |
32745759 | Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses. | 2020 Oct |
2 |
| 25 |
32898795 | Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy. | 2020 Dec 15 |
1 |
| 26 |
32999149 | Design, Synthesis and Biological Evaluation of the Quinazoline Derivatives as L858R/T790M/C797S Triple Mutant Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. | 2020 |
1 |
| 27 |
30600209 | Discovery of new quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors and their anticancer activities - Part 1. | 2019 Feb 15 |
2 |
| 28 |
30835140 | Design, synthesis and biological evaluation of novel 4-anlinoquinazoline derivatives as EGFR inhibitors with the potential to inhibit the gefitinib-resistant nonsmall cell lung cancers. | 2019 Dec |
1 |
| 29 |
31121559 | Synthesis and in vitro anticancer evaluation of some fused indazoles, quinazolines and quinolines as potential EGFR inhibitors. | 2019 Aug |
1 |
| 30 |
31424613 | Targeting an EGFR Water Network with 4-Anilinoquin(az)oline Inhibitors for Chordoma. | 2019 Oct 4 |
2 |
| 31 |
31436470 | Evaluation of EGFR-TK Expression with a 99mTc-Labeled Complex Bearing Quinazoline Pharmacophore. | 2019 Nov |
1 |
| 32 |
29094267 | Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents. | 2018 Jan |
2 |
| 33 |
29098884 | Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance. | 2018 Dec |
2 |
| 34 |
29369008 | Computational screening, ensemble docking and pharmacophore analysis of potential gefitinib analogues against epidermal growth factor receptor. | 2018 Feb |
2 |
| 35 |
29421573 | 6,7-Dimorpholinoalkoxy quinazoline derivatives as potent EGFR inhibitors with enhanced antiproliferative activities against tumor cells. | 2018 Mar 10 |
1 |
| 36 |
29482151 | New acrylamide-substituted quinazoline derivatives with enhanced potency for the treatment of EGFR T790M-mutant non-small-cell lung cancers. | 2018 Apr |
2 |
| 37 |
29523467 | Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors. | 2018 May 1 |
3 |
| 38 |
29775935 | Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3-dihydro-indole or 1,2,3,4-tetrahydroquinoline as potential EGFR inhibitors. | 2018 Jun 25 |
1 |
| 39 |
30065769 | Structure based design and anti-breast cancer evaluation of some novel 4-anilinoquinazoline derivatives as potential epidermal growth factor receptor inhibitors. | 2018 Aug |
2 |
| 40 |
30455856 | Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors. | 2018 |
2 |
| 41 |
30556027 | Synthesis of Triazole-Substituted Quinazoline Hybrids for Anticancer Activity and a Lead Compound as the EGFR Blocker and ROS Inducer Agent. | 2018 Nov 30 |
2 |
| 42 |
30607149 | Exploring the interaction between epidermal growth factor receptor tyrosine kinase and some of the synthesized inhibitors using combination of in-silico and in-vitro cytotoxicity methods. | 2018 Dec |
2 |
| 43 |
28092860 | Design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs. | 2017 Feb 15 |
1 |
| 44 |
28291344 | First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents. | 2017 Apr 13 |
1 |
| 45 |
28363995 | Response Heterogeneity of EGFR and HER2 Exon 20 Insertions to Covalent EGFR and HER2 Inhibitors. | 2017 May 15 |
3 |
| 46 |
28428040 | Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors. | 2017 Jun 15 |
1 |
| 47 |
28478927 | Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors. | 2017 Jun 15 |
1 |
| 48 |
29096097 | Novel quinoline-3-carboxamides (Part 2): Design, optimization and synthesis of quinoline based scaffold as EGFR inhibitors with potent anticancer activity. | 2017 Dec |
1 |
| 49 |
29295519 | Design and Discovery of Quinazoline- and Thiourea-Containing Sorafenib Analogs as EGFR and VEGFR-2 Dual TK Inhibitors. | 2017 Dec 23 |
2 |
| 50 |
26613384 | Novel Quinazoline Derivatives Bearing Various 4-Aniline Moieties as Potent EGFR Inhibitors with Enhanced Activity Against NSCLC Cell Lines. | 2016 Apr |
3 |