| 1 |
35264561 | Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. | 2022 Mar 9 |
2 |
| 2 |
33379119 | Deacetylation-activated construction of single quantum dot-based nanosensor for sirtuin 1 assay. | 2021 Mar 1 |
1 |
| 3 |
33854041 | Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis. | 2021 Apr 14 |
1 |
| 4 |
33859801 | A Set of Highly Sensitive Sirtuin Fluorescence Probes for Screening Small-Molecular Sirtuin Defatty-Acylase Inhibitors. | 2021 Apr 8 |
1 |
| 5 |
33880981 | Promising drug discovery strategies for sirtuin modulators: what lessons have we learnt? | 2021 Aug |
1 |
| 6 |
34055852 | Mechanisms and Neuroprotective Activities of Stigmasterol Against Oxidative Stress-Induced Neuronal Cell Death via Sirtuin Family. | 2021 |
2 |
| 7 |
34214583 | Sirtuin 1 as the mechanism of action of agents used in the diabetes mellitus pharmacotherapy. | 2021 Sep 15 |
2 |
| 8 |
34456745 | Regulation of NADPH Oxidase-Mediated Superoxide Production by Acetylation and Deacetylation. | 2021 |
1 |
| 9 |
31544977 | Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. | 2020 Mar |
1 |
| 10 |
31576013 | Proteasome inhibitor induced SIRT1 deacetylates GLI2 to enhance hedgehog signaling activity and drug resistance in multiple myeloma. | 2020 Jan |
1 |
| 11 |
32154934 | SIRT1 Regulates N6 -Methyladenosine RNA Modification in Hepatocarcinogenesis by Inducing RANBP2-Dependent FTO SUMOylation. | 2020 Dec |
1 |
| 12 |
32332759 | FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku. | 2020 Apr 24 |
1 |
| 13 |
32371394 | Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants. | 2020 Jun 19 |
1 |
| 14 |
32518374 | WSTF acetylation by MOF promotes WSTF activities and oncogenic functions. | 2020 Jul |
1 |
| 15 |
32528730 | SIRT1 directly activates autophagy in human chondrocytes. | 2020 |
1 |
| 16 |
30623565 | Inhibition of nucleolar stress response by Sirt1: A potential mechanism of acetylation-independent regulation of p53 accumulation. | 2019 Apr |
2 |
| 17 |
30710424 | Metformin and tenovin-6 synergistically induces apoptosis through LKB1-independent SIRT1 down-regulation in non-small cell lung cancer cells. | 2019 Apr |
1 |
| 18 |
30858544 | Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma. | 2019 Jun |
1 |
| 19 |
31066329 | Noncatalytic functions of IPMK are essential for activation of autophagy and liver regeneration. | 2019 Aug |
1 |
| 20 |
31282985 | Research progress on SIRT1 and sepsis. | 2019 Nov |
1 |
| 21 |
31291457 | A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. | 2019 Sep 19 |
2 |
| 22 |
31722219 | CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation. | 2019 Nov 12 |
1 |
| 23 |
29308302 | Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype. | 2018 |
1 |
| 24 |
29330620 | Impact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation. | 2018 Apr |
1 |
| 25 |
29574020 | SIRT1 and microRNAs: The role in breast, lung and prostate cancers. | 2018 Jun 1 |
2 |
| 26 |
30028960 | Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis. | 2018 Oct |
1 |
| 27 |
30146412 | SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. | 2018 Sep 6 |
1 |
| 28 |
30327428 | Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage. | 2018 Dec 7 |
8 |
| 29 |
28017215 | Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report. | 2017 Jan 15 |
1 |
| 30 |
28191886 | Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. | 2017 Mar |
5 |
| 31 |
28893905 | Lysine acetylation stoichiometry and proteomics analyses reveal pathways regulated by sirtuin 1 in human cells. | 2017 Nov 3 |
1 |
| 32 |
29118980 | SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development. | 2017 |
2 |
| 33 |
27226597 | Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins. | 2016 Jul 8 |
2 |
| 34 |
27259994 | Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1. | 2016 Jun 28 |
1 |
| 35 |
27819261 | SIRT1 deacetylates the cardiac transcription factor Nkx2.5 and inhibits its transcriptional activity. | 2016 Nov 7 |
1 |
| 36 |
24940804 | High-mobility group box 1 is a novel deacetylation target of Sirtuin1. | 2015 Jan |
1 |
| 37 |
25452565 | Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. | 2015 Jan 1 |
2 |
| 38 |
25529796 | Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. | 2015 Jan |
1 |
| 39 |
25815376 | Endosome traffic machinery meets the p53-p21 axis. | 2015 |
1 |
| 40 |
26134520 | Crystallographic structure of a small molecule SIRT1 activator-enzyme complex. | 2015 Jul 2 |
2 |
| 41 |
26177453 | SIRT1 Interacts with and Deacetylates ATP6V1B2 in Mature Adipocytes. | 2015 |
1 |
| 42 |
26297866 | SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights. | 2015 Nov |
1 |
| 43 |
23604120 | Sorting out functions of sirtuins in cancer. | 2014 Mar 27 |
1 |
| 44 |
23873758 | Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation. | 2014 Feb |
1 |
| 45 |
24038750 | Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation. | 2014 Jan |
1 |
| 46 |
24397908 | SIRT1 is decreased during relapses in patients with multiple sclerosis. | 2014 Apr |
1 |
| 47 |
24702180 | Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells. | 2014 Jun |
1 |
| 48 |
24747578 | Quantitative insights for the design of substrate-based SIRT1 inhibitors. | 2014 Aug 1 |
2 |
| 49 |
25040736 | SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence. | 2014 Oct |
1 |
| 50 |
25055869 | Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription. | 2014 Dec 15 |
1 |