Gefitinib

epidermal growth factor receptor ; Rattus norvegicus







36 Article(s)
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1 35183859 Discovery of EGFR-Targeted Environment-Sensitive fluorescent probes for cell imaging and efficient tumor detection. 2022 Apr 2
2 33269993 Comprehensive identification, fragmentation pattern, and metabolic pathways of gefitinib metabolites via UHPLC-Q-TOF-MS/MS: in vivo study of rat plasma, urine, bile, and faeces. 2021 Mar 3
3 33849825 [Establishment of animal models of epidermal growth factor receptor inhibitor-related rashes]. 2021 Mar 25 1
4 34830377 Cell Behavior of Non-Small Cell Lung Cancer Is at EGFR and MicroRNAs Hands. 2021 Nov 19 3
5 31264901 Augmented Pulmonary Vasoconstrictor Reactivity after Chronic Hypoxia Requires Src Kinase and Epidermal Growth Factor Receptor Signaling. 2020 Jan 2
6 32111605 EGFR Signaling Causes Morphine Tolerance and Mechanical Sensitization in Rats. 2020 Mar/Apr 3
7 32370496 EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies. 2020 Jul 20 5
8 33025329 Gefitinib-Induced Cutaneous Toxicities in Brown Norway Rats Are Associated with Macrophage Infiltration. 2020 Dec 4
9 29228391 Arsenic Attenuates Heparin-Binding EGF-Like Growth Factor/EGFR Signaling That Promotes Matrix Metalloprotease 9-Dependent Astrocyte Damage in the Developing Rat Brain. 2018 Apr 1 3
10 29396379 Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration. 2018 Apr 3
11 26677863 Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis. 2016 Sep 2
12 27669229 The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models. 2016 Sep 23 4
13 25788532 EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy. 2015 Nov 1
14 23559083 Thyroid cancer cell resistance to gefitinib depends on the constitutive oncogenic activation of the ERK pathway. 2013 Jun 4
15 23632456 ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions. 2013 Apr 30 1
16 21982874 Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. 2012 Feb 2
17 22450006 Epidermal growth factor receptor-tyrosine kinase inhibitor (gefitinib) augments pneumonitis, but attenuates lung fibrosis in response to radiation injury in rats. 2012 4
18 22967907 Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells. 2012 Sep 11 2
19 21369704 Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers. 2011 May 1
20 21887704 The critical role of the epidermal growth factor receptor in endochondral ossification. 2011 Nov 1
21 21925118 Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells. 2011 Oct 2
22 19850946 Role of epidermal growth factor inhibition in experimental pulmonary hypertension. 2010 Jan 15 1
23 20962455 Antipsychotic potential of quinazoline ErbB1 inhibitors in a schizophrenia model established with neonatal hippocampal lesioning. 2010 1
24 18180313 Testosterone-stimulated growth of the rat prostate may be driven by tissue hypoxia and hypoxia-inducible factor-1alpha. 2008 Jan 2
25 18375820 Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes. 2008 Apr 2
26 18413814 Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. 2008 Apr 15 2
27 18519677 RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR. 2008 Jun 1 1
28 18630690 [Effect of gefinitib on airway mucus hypersecretion induced by acrolein in rats]. 2008 Mar 4
29 16488438 Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model. 2006 Jul 3
30 16988945 Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib. 2006 Dec 1 1
31 17003482 Inhibition of intrahepatic bile duct dilation of the polycystic kidney rat with a novel tyrosine kinase inhibitor gefitinib. 2006 Oct 2
32 17043666 Inhibition of EGFR signaling abrogates smooth muscle proliferation resulting from sustained distension of the urinary bladder. 2006 Dec 1
33 15660382 Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis. 2005 Feb 4
34 15033924 Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition. 2004 May 1
35 12219038 A serum factor after intestinal resection stimulates epidermal growth factor receptor signaling and proliferation in intestinal epithelial cells. 2002 Aug 1
36 11479217 Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors. 2001 Aug 1 2