Title : The critical role of the epidermal growth factor receptor in endochondral ossification.

Pub. Date : 2011 Nov

PMID : 21887704






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we show that administration of an EGFR-specific small-molecule inhibitor, gefitinib, into 1-month-old rats for 7 days produced profound defects in long bone growth plate cartilage characterized by epiphyseal growth plate thickening and massive accumulation of hypertrophic chondrocytes. Gefitinib epidermal growth factor receptor Rattus norvegicus