Pub. Date : 2008 Mar
PMID : 18630690
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gefitinib also reduced the expression of EGFR in the lungs. | Gefitinib | epidermal growth factor receptor | Rattus norvegicus |
| 2 | CONCLUSION: Acrolein increases the expression of MUC5AC through activating EGFR, which indicates that EGFR-TKI such as gefitinib can be useful in the treatment of mucus hypersecretion by regulating the signal transduction pathways of EGFR. | Gefitinib | epidermal growth factor receptor | Rattus norvegicus |
| 3 | CONCLUSION: Acrolein increases the expression of MUC5AC through activating EGFR, which indicates that EGFR-TKI such as gefitinib can be useful in the treatment of mucus hypersecretion by regulating the signal transduction pathways of EGFR. | Gefitinib | epidermal growth factor receptor | Rattus norvegicus |
| 4 | CONCLUSION: Acrolein increases the expression of MUC5AC through activating EGFR, which indicates that EGFR-TKI such as gefitinib can be useful in the treatment of mucus hypersecretion by regulating the signal transduction pathways of EGFR. | Gefitinib | epidermal growth factor receptor | Rattus norvegicus |