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methylenetetrahydrofolate reductase ; Homo sapiens







88 Article(s)
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1 35046699 Association Between SNPs in the One-Carbon Metabolism Pathway and the Risk of Female Breast Cancer in a Chinese Population. 2022 1
2 33411826 Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densities. 2021 2
3 33476699 Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain. 2021 Apr 2
4 33639933 Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India. 2021 Feb 27 2
5 33802362 Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphism and Infant's Anthropometry at Birth. 2021 Mar 3 1
6 34502300 MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA. 2021 Aug 30 2
7 34960114 Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks. 2021 Dec 20 2
8 31812845 One‑carbon metabolism factor MTHFR variant is associated with saccade latency in Spinocerebellar Ataxia type 2. 2020 Feb 15 1
9 31968288 Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach. 2020 Jan - Apr 2
10 32330571 Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation. 2020 Jun 1
11 32379616 Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia. 2020 Jul 1 2
12 32393056 Polymorphisms of genes required for methionine synthesis and DNA methylation influence mitochondrial DNA methylation. 2020 Jun 1
13 33364984 Roles of 5,10-Methylenetetrahydrofolate Reductase C677T Polymorphisms in First-Episode, Drug-Naive Adult Patients With Depression. 2020 2
14 30606816 MTHFR C677T polymorphism increases MTX sensitivity via the inhibition of S-adenosylmethionine and de novo purine synthesis. 2019 Jan 31 1
15 30862944 Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase. 2019 Mar 12 2
16 31216671 Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer. 2019 Jun 18 2
17 31370354 Association of Polymorphisms in Genes Involved in One-Carbon Metabolism with MTHFR Methylation Levels. 2019 Jul 31 4
18 31902858 Association of Intake Folate and Related Gene Polymorphisms with Breast Cancer. 2019 2
19 29185200 The MTHFR polymorphism affect the susceptibility of HCC and the prognosis of HCC liver transplantation. 2018 Apr 2
20 29564022 No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation. 2018 2
21 29627528 The association between donor genetic variations in one-carbon metabolism pathway genes and hepatitis B recurrence after liver transplantation. 2018 Jul 15 1
22 30018733 Gene-environment interactions and predictors of breast cancer in family-based multi-ethnic groups. 2018 Jun 26 2
23 30397195 Methylenetetrahydrofolate reductase and psychiatric diseases. 2018 Nov 5 2
24 28871711 Analysis of the rs13306560 functional variant in the promoter region of the MTHFR gene in sporadic Parkinson´s disease. 2017 Aug 1
25 26759827 Quantification of gene-specific methylation of DNMT3B and MTHFR using sequenom EpiTYPER®. 2016 Mar 1
26 27173682 Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis. 2016 Aug 1
27 27541683 Population-level diversity in the association of genetic polymorphisms of one-carbon metabolism with breast cancer risk. 2016 Oct 1
28 27560137 Genetic Variation of Methylenetetrahydrofolate Reductase (MTHFR) and Thymidylate Synthase (TS) Genes Is Associated with Idiopathic Recurrent Implantation Failure. 2016 1
29 27854316 Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing. 2016 Nov 16 1
30 25604861 Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case-control study in the Greek-Cypriot female population. 2015 Mar 1
31 26079324 Methylation analysis of multiple genes in blood DNA of Alzheimer's disease and healthy individuals. 2015 Jul 23 1
32 26485042 Gene-specific DNA methylation of DNMT3B and MTHFR and colorectal adenoma risk. 2015 Dec 2
33 24533714 Intraindividual somatic variations in MTHFR gene polymorphisms in relation to colon cancer. 2014 Feb 1
34 25012419 The one-carbon-cycle and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in recurrent major depressive disorder; influence of antidepressant use and depressive state? 2014 Sep 1
35 23896051 Increased susceptibility to mild neonatal stress in MTHFR deficient mice. 2013 Sep 15 2
36 24101362 Effects of methionine synthase and methylenetetrahydrofolate reductase gene polymorphisms on markers of one-carbon metabolism. 2013 Nov 1
37 22052259 MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung. 2012 Sep 1 2
38 22373582 Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women. 2012 Aug 1
39 22946297 [Stoichiometric model of folate-dependent metabolism of one-carbon units in human placenta]. 2012 Jul-Aug 1
40 21123458 MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. 2011 Feb 1
41 21178087 Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans. 2011 Feb 2
42 21185933 Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability? 2011 Nov 1
43 21302350 Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples. 2011 Mar 2
44 21980405 A hypomethylating variant of MTHFR, 677C>T, blunts the neural response to errors in patients with schizophrenia and healthy individuals. 2011 2
45 22039442 Comprehensive evaluation of one-carbon metabolism pathway gene variants and renal cell cancer risk. 2011 1
46 20552676 The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder. 2010 Oct 5 2
47 20692813 Gene-wide association study between the methylenetetrahydrofolate reductase gene (MTHFR) and schizophrenia in the Japanese population, with an updated meta-analysis on currently available data. 2010 Dec 2
48 18983889 C677T methylenetetrahydrofolate reductase gene polymorphisms in bipolar disorder: an association study in the Chinese population and a meta-analysis of genetic association studies. 2009 Jan 2 1
49 19144510 C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation. 2009 May 2
50 19240236 DNA promoter methylation in breast tumors: no association with genetic polymorphisms in MTHFR and MTR. 2009 Mar 2