Title : DNA promoter methylation in breast tumors: no association with genetic polymorphisms in MTHFR and MTR.

Pub. Date : 2009 Mar

PMID : 19240236






2 Functional Relationships(s)
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1 We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in the one-carbon metabolism, may alter DNA methylation levels and thus influence DNA methylation in breast cancer. Carbon methylenetetrahydrofolate reductase Homo sapiens
2 We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in the one-carbon metabolism, may alter DNA methylation levels and thus influence DNA methylation in breast cancer. Carbon methylenetetrahydrofolate reductase Homo sapiens