Title : MTHFR C677T polymorphism increases MTX sensitivity via the inhibition of S-adenosylmethionine and de novo purine synthesis.

Pub. Date : 2019 Jan 31

PMID : 30606816






1 Functional Relationships(s)
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1 MTHFR-C677T altered protein turnover and folate mediated 1-carbon metabolic fluxes in lymphoblasts with and without MTX. Carbon methylenetetrahydrofolate reductase Homo sapiens