1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

caspase 3 ; Mus musculus







21 Article(s)
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1 33925146 The Neuroprotective Effects of GPR4 Inhibition through the Attenuation of Caspase Mediated Apoptotic Cell Death in an MPTP Induced Mouse Model of Parkinson's Disease. 2021 Apr 28 1
2 32926778 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Parkinson's Disease in Mouse: Potential Association between Neurotransmitter Disturbance and Gut Microbiota Dysbiosis. 2020 Oct 21 2
3 31690718 Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson's disease. 2019 Nov 5 1
4 29264673 Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson's disease. 2018 Jun 1
5 29588573 Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway. 2018 1
6 28527958 Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-κB signaling pathway. 2017 Jul 25 1
7 25730317 Lutein protects dopaminergic neurons against MPTP-induced apoptotic death and motor dysfunction by ameliorating mitochondrial disruption and oxidative stress. 2016 Jul 1
8 26477638 Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in the MPTP-induced mouse model of Parkinson's disease: Involvement of reactive oxygen species-mediated JNK, P38 and mitochondrial pathways. 2015 Nov 15 1
9 24795109 The role of nitric oxide on visual-evoked potentials in MPTP-induced Parkinsonism in mice. 2014 Jun 1
10 23184853 Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease. 2013 Mar 1
11 23933227 Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. 2013 Dec 1
12 22178176 Dangguijakyak-san protects dopamine neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity under postmenopausal conditions. 2012 Feb 15 1
13 21291942 Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. 2011 Jun 1 1
14 21562748 The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice. 2011 Oct 1
15 20937256 Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice. 2010 Nov 12 7
16 19861252 [P38MAPK pathway regulates COX-2 and caspase-3 expression in a mouse model of Parkinson disease]. 2009 Oct 1
17 18577498 Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra. 2008 Aug 1
18 16957581 Evidence of apoptosis in the subventricular zone and rostral migratory stream in the MPTP mouse model of Parkinson disease. 2006 Sep 1
19 12579817 [Possible mechanisms of the protective effect of ginsenoside Rg1 on apoptosis in substantia nigra neurons]. 2002 Apr 1
20 11295768 Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. 2001 Mar 3
21 11739563 Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. 2001 Dec 15 2