Title : 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Parkinson's Disease in Mouse: Potential Association between Neurotransmitter Disturbance and Gut Microbiota Dysbiosis.

Pub. Date : 2020 Oct 21

PMID : 32926778






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the current study, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced a characteristic PD neurobehavior changes accompanied by increased alpha-synuclein, apoptotic protein Bim, cleaved caspase-3 and decreased expression of tyrosine hydroxylase (TH). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine caspase 3 Mus musculus
2 In the current study, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced a characteristic PD neurobehavior changes accompanied by increased alpha-synuclein, apoptotic protein Bim, cleaved caspase-3 and decreased expression of tyrosine hydroxylase (TH). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine caspase 3 Mus musculus