Polyglutamic Acid

folylpolyglutamate synthase ; Homo sapiens







20 Article(s)
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1 27620954 Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer. 2016 Sep 1
2 23949282 Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells. 2013 Sep 2
3 18025275 Effects of folate and folylpolyglutamyl synthase modulation on chemosensitivity of breast cancer cells. 2007 Nov 2
4 16707018 Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cells. 2006 May 17 2
5 15542523 Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate. 2004 Dec 2
6 10413425 Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. 1999 Jul 21 2
7 10507318 Variable expression of the folylpolyglutamate synthetase gene at the level of mRNA transcription in human leukemia cell lines sensitive, or made resistant, to various antifolate drugs. 1999 Aug 1
8 10626793 Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolites. 1999 Dec 15 2
9 9306433 gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias. 1997 3
10 7651366 Substrate specificity of mammalian folylpolyglutamate synthetase for 5,10-dideazatetrahydrofolate analogs. 1995 Aug 2
11 7517720 Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. 1994 Jul 15 1
12 8144562 Role of folylpolyglutamate synthetase in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug. 1994 Apr 1 1
13 8408019 Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism. 1993 Oct 15 1
14 8408021 Regulation of folate and one-carbon metabolism in mammalian cells. IV. Role of folylpoly-gamma-glutamate synthetase in methotrexate metabolism and cytotoxicity. 1993 Oct 15 2
15 1435744 Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development. 1992 Oct 2
16 3431589 Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetase. 1987 1
17 3619447 Human liver folylpolyglutamate synthetase: biochemical characterization and interactions with folates and folate antagonists. 1987 Aug 1 1
18 3466358 Characterization of human folylpolyglutamate synthetase expressed in Chinese hamster ovary cells. 1986 Nov 1
19 3812977 In situ autoradiographic detection of folylpolyglutamate synthetase activity. 1986 Nov 1 1
20 3873989 Folate analogues as substrates of mammalian folylpolyglutamate synthetase. 1985 Jul 1