Sitagliptin Phosphate

dipeptidylpeptidase 4 ; Mus musculus







93 Article(s)
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1 34392748 The role of dipeptidyl peptidase-IV in abdominal aortic aneurysm pathogenesis: A systematic review. 2022 Feb 1
2 35163991 Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease. 2022 Jan 22 1
3 35203674 Minimum Effective Dose of DPP-4 Inhibitors for Treating Early Stages of Diabetic Retinopathy in an Experimental Model. 2022 Feb 16 1
4 35364117 A novel therapeutic combination of sitagliptin and melatonin regenerates pancreatic β-cells in mouse and human islets. 2022 Aug 2
5 35620578 Sitagliptin Alleviates Radiation-Induced Intestinal Injury by Activating NRF2-Antioxidant Axis, Mitigating NLRP3 Inf--lammasome Activation, and Reversing Gut Microbiota Disorder. 2022 2
6 33148870 Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells. 2021 Mar 1 6
7 33258801 Combined use of GABA and sitagliptin promotes human β-cell proliferation and reduces apoptosis. 2021 Feb 2
8 33513866 DPP4 Inhibitor Sitagliptin Enhances Lymphocyte Recruitment and Prolongs Survival in a Syngeneic Ovarian Cancer Mouse Model. 2021 Jan 27 2
9 33735157 Functional Dissection of CD26 and Its Pharmacological Inhibition by Sitagliptin During Skin Wound Healing. 2021 Mar 18 4
10 33781961 Sitagliptin, a dipeptidyl peptidase-4 inhibitor, attenuates apoptosis of vascular smooth muscle cells and reduces atherosclerosis in diabetic apolipoprotein E-deficient mice. 2021 Oct 3
11 33975617 The effect of dipeptidyl peptidase IV on disease-associated microglia phenotypic transformation in epilepsy. 2021 May 11 2
12 34493714 Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway. 2021 Sep 7 7
13 34497344 Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice. 2021 Sep 8 2
14 34631556 Antidiabetic DPP-4 Inhibitors Reprogram Tumor Microenvironment That Facilitates Murine Breast Cancer Metastasis Through Interaction With Cancer Cells via a ROS-NF-кB-NLRP3 Axis. 2021 1
15 34944588 Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy. 2021 Nov 26 2
16 31350829 Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis. 2020 Jan 1
17 32281218 Sitagliptin ameliorates renal tubular injury in diabetic kidney disease via STAT3-dependent mitochondrial homeostasis through SDF-1α/CXCR4 pathway. 2020 Jun 2
18 32398684 Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2. 2020 Nov 2
19 32430013 Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis. 2020 May 19 1
20 32724076 Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans. 2020 Jul 28 1
21 32774687 Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice. 2020 2
22 33126761 Pyrazole Incorporated New Thiosemicarbazones: Design, Synthesis and Investigation of DPP-4 Inhibitory Effects. 2020 Oct 28 1
23 33182020 Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice. 2020 Nov 2
24 30520247 Combined effect of GABA and glucagon-like peptide-1 receptor agonist on cytokine-induced apoptosis in pancreatic β-cell line and isolated human islets. 2019 Jul 1
25 30696428 Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes. 2019 Jan 29 1
26 30707388 DPP-4 Inhibition Leads to Decreased Pancreatic Inflammatory Profile and Increased Frequency of Regulatory T Cells in Experimental Type 1 Diabetes. 2019 Apr 1
27 30778250 Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth. 2019 Mar 1
28 30940309 The dipeptidyl peptidase-4 inhibitor sitagliptin ameliorates renal injury in type 1 diabetic mice via inhibiting the TGF-β/Smad signal pathway. 2019 Apr 1 2
29 31077717 Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice. 2019 Jul 1 2
30 31474716 Diurnal Variation of Sitagliptin-Induced Pharmacological Effects in C57BL/6J Mice. 2019 1
31 31827684 DPP4 Inhibitor Attenuates Severe Acute Pancreatitis-Associated Intestinal Inflammation via Nrf2 Signaling. 2019 1
32 28799229 Sitagliptin-mediated preservation of endothelial progenitor cell function via augmenting autophagy enhances ischaemic angiogenesis in diabetes. 2018 Jan 2
33 29136947 The effect of the dipeptidyl peptidase-4 inhibitor sitagliptin on gentamicin nephrotoxicity in mice. 2018 Jan 1
34 29203510 Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery. 2018 Feb 1
35 29531541 Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling. 2018 1
36 30028901 A dipeptidyl peptidase-4 inhibitor promotes wound healing in normoglycemic mice by modulating keratinocyte activity. 2018 Oct 2
37 30116740 DPP-4 Inhibitor Sitagliptin Improves Cardiac Function and Glucose Homeostasis and Ameliorates β-Cell Dysfunction Together with Reducing S6K1 Activation and IRS-1 and IRS-2 Degradation in Obesity Female Mice. 2018 2
38 30123267 Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice. 2018 2
39 30186862 Neuroprotective Activity of Sitagliptin via Reduction of Neuroinflammation beyond the Incretin Effect: Focus on Alzheimer's Disease. 2018 1
40 30188745 DPP4 inhibition by sitagliptin attenuates LPS-induced lung injury in mice. 2018 Nov 1 4
41 30202822 Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells. 2018 Sep 2
42 30343953 Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents. 2018 Dec 15 1
43 28322746 Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes. 2017 May 15 2
44 28334048 Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity. 2017 1
45 28355570 Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis. 2017 Mar 28 1
46 28442582 LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice. 2017 Jul 1
47 28676760 Combined Oral Administration of GABA and DPP-4 Inhibitor Prevents Beta Cell Damage and Promotes Beta Cell Regeneration in Mice. 2017 1
48 28703769 Glycosaminoglycans Regulate CXCR3 Ligands at Distinct Levels: Protection against Processing by Dipeptidyl Peptidase IV/CD26 and Interference with Receptor Signaling. 2017 Jul 13 1
49 28713268 Sitagliptin, An Anti-diabetic Drug, Suppresses Estrogen Deficiency-Induced OsteoporosisIn Vivo and Inhibits RANKL-Induced Osteoclast Formation and Bone Resorption In Vitro. 2017 2
50 28943949 Sitagliptin, a dipeptidyl peptidase-4 inhibitor, suppresses CXCL5 and SDF-1 and does not accelerate intestinal neoplasia formation in ApcMin/+ mice fed a high-fat diet. 2017 Oct 1