Pub. Date : 2018 Nov 1
PMID : 30188745
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DPP4 inhibition by sitagliptin attenuates LPS-induced lung injury in mice. | Sitagliptin Phosphate | dipeptidylpeptidase 4 | Mus musculus |
| 2 | In vivo, sitagliptin reduced serum DPP4 activity, bronchoalveolar lavage protein concentration, cell number, and proinflammatory cytokine levels after LPS and alleviated histological findings of lung injury. | Sitagliptin Phosphate | dipeptidylpeptidase 4 | Mus musculus |
| 3 | LPS decreased the expression levels of CD26/DPP4 on pulmonary epithelial cells and PVECs isolated from mouse lungs, and the effect was partially reversed by sitagliptin. | Sitagliptin Phosphate | dipeptidylpeptidase 4 | Mus musculus |
| 4 | LPS decreased the expression levels of CD26/DPP4 on pulmonary epithelial cells and PVECs isolated from mouse lungs, and the effect was partially reversed by sitagliptin. | Sitagliptin Phosphate | dipeptidylpeptidase 4 | Mus musculus |