Fatty Acids

AKT serine/threonine kinase 1 ; Homo sapiens







46 Article(s)
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1 35046108 Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation. 2022 May 4 1
2 35092683 Corrigendum to 'Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells'. 2022 Jan 29 1
3 35157107 Differential effects of single fatty acids and fatty acid mixtures on the phosphoinositide 3-kinase/Akt/eNOS pathway in endothelial cells. 2022 Feb 14 6
4 35235781 Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer. 2022 Mar 1 1
5 33716662 Integration of Nutrient Sensing in Fish Hypothalamus. 2021 1
6 33755174 Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells. 2021 Sep 11 1
7 34119888 A scalable and sensitive steatosis chip with long-term perfusion of in situ differentiated HepaRG organoids. 2021 Aug 1
8 34718375 Epicatechin gallate prevents the de novo synthesis of fatty acid and the migration of prostate cancer cells. 2021 Dec 8 1
9 31746305 Coumarin-Fatty Acid Conjugates as Potential ERα/AKT-1 Antagonists for ER Positive Breast Cancer. 2020 1
10 31819192 Reprogramming of fatty acid metabolism in cancer. 2020 Jan 1
11 32072901 Amino Acids Regulate Glycolipid Metabolism and Alter Intestinal Microbial Composition. 2020 1
12 32194897 Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis. 2020 2
13 32312965 Inhibition of collagen XI alpha 1-induced fatty acid oxidation triggers apoptotic cell death in cisplatin-resistant ovarian cancer. 2020 Apr 20 2
14 32481546 Epidermal Growth Factor Stimulates Fatty Acid Synthesis Mainly via PLC-γ1/Akt Signaling Pathway in Dairy Goat Mammary Epithelial Cells. 2020 May 28 2
15 30339883 Oxidative stress mediated by lipid metabolism contributes to high glucose-induced senescence in retinal pigment epithelium. 2019 Jan 1
16 30985894 Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway†. 2019 Jul 1 1
17 31332162 Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes. 2019 Jul 22 1
18 29323924 Akt Serine/Threonine Kinase 1 Regulates de Novo Fatty Acid Synthesis through the Mammalian Target of Rapamycin/Sterol Regulatory Element Binding Protein 1 Axis in Dairy Goat Mammary Epithelial Cells. 2018 Feb 7 1
19 29720254 Concurrent interactome and metabolome analysis reveals role of AKT1 in central carbon metabolism. 2018 May 2 1
20 27878243 Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells. 2017 Jan 1
21 28273470 Dietary Fat Inflames CD4+ T Cell Memory in Obesity. 2017 Mar 7 1
22 26698173 Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. 2016 Feb 5 2
23 26956906 Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes. 2016 Aug 3
24 27104558 Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. 2016 Apr 19 1
25 27292634 Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics. 2016 Jun 21 1
26 25535334 Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes. 2015 Mar 1
27 25793412 Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells. 2015 1
28 25938832 [Role of PI3K/Akt pathway in endoplasmic reticulum stress and apoptosis induced by saturated fatty acid in human steatotic hepatocytes]. 2015 Mar 2
29 25957914 Downregulation of microRNA-451 in non-alcoholic steatohepatitis inhibits fatty acid-induced proinflammatory cytokine production through the AMPK/AKT pathway. 2015 Jul 2
30 25964336 Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes. 2015 May 26 1
31 26282231 CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways. 2015 Dec 1
32 26335364 Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells. 2015 Dec 1
33 22923231 Genetic downregulation of receptor-interacting protein 140 uncovers the central role of Akt signalling in the regulation of fatty acid oxidation in skeletal muscle cells. 2013 Feb 1
34 23671091 Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. 2013 May 28 1
35 23794138 Hydrolysis products generated by lipoprotein lipase and endothelial lipase differentially impact THP-1 macrophage cell signalling pathways. 2013 Aug 1
36 23989724 Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment. 2013 Dec 1
37 20017192 IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis. 2010 Mar 1
38 19477653 Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3beta pathway. 2009 Jul 1 2
39 19480565 Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signalling in colorectal cancer cells. 2009 Jul 1
40 17299765 IGF-1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination. 2007 Apr 15 1
41 18070348 Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells. 2007 Dec 10 1
42 16452198 Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer. 2006 Feb 1 1
43 15806154 The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. 2005 Jun 16 3
44 16007182 PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. 2005 Sep 29 6
45 15068229 Fatty acids differentially modulate insulin-stimulated endothelial nitric oxide production by an Akt-independent pathway. 2004 Mar 4
46 12393870 Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1). 2002 Dec 20 1