Title : IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis.

Pub. Date : 2010 Mar

PMID : 20017192






1 Functional Relationships(s)
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1 This protection is intrinsic, not due to changes in complement regulatory proteins, and requires activation of Akt and sterol receptor element binding protein-1 (SREBP-1), which regulates fatty acid and phospholipid synthesis. Fatty Acids AKT serine/threonine kinase 1 Homo sapiens