7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

AKT serine/threonine kinase 1 ; Homo sapiens







8 Article(s)
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1 33851497 Upregulated lnc-HZ02 and miR-hz02 inhibited migration and invasion by downregulating the FAK/SRC/PI3K/AKT pathway in BPDE-treated trophoblast cells. 2021 Jun 2
2 30727793 Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1α (SDF-1α). 2019 Mar 1
3 30011042 Benzo[a]Pyrene-7, 8-Diol-9, 10-Epoxide Suppresses the Migration and Invasion of Human Extravillous Trophoblast Swan 71 Cells Due to the Inhibited Filopodia Formation and Down-Regulated PI3K/AKT/CDC42/PAK1 Pathway Mediated by the Increased miR-194-3p. 2018 Nov 1 2
4 28529061 Benzo[a]pyrene-7,8-diol-9,10-epoxide suppresses the migration and invasion of human extravillous trophoblast HTR-8/SVneo cells by down-regulating MMP2 through inhibition of FAK/SRC/PI3K/AKT pathway. 2017 Jul 1 4
5 24431215 Low-dose benzo(a)pyrene and its epoxide metabolite inhibit myogenic differentiation in human skeletal muscle-derived progenitor cells. 2014 Apr 2
6 22457794 MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation. 2012 1
7 19801633 Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis. 2009 Nov 27 1
8 16774943 PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells. 2006 Nov 10