Pub. Date : 2021 Jun
PMID : 33851497
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upregulated lnc-HZ02 and miR-hz02 inhibited migration and invasion by downregulating the FAK/SRC/PI3K/AKT pathway in BPDE-treated trophoblast cells. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | If trophoblast cells are exposed to BPDE, both miR-hz02 and lnc-HZ02 are upregulated, which reduce the level of HuR, weaken the interactions of HuR with FAK mRNA, downregulate FAK level and the FAK/SRC/PI3K/AKT pathway, and finally inhibit cell migration and invasion. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | AKT serine/threonine kinase 1 | Homo sapiens |