Polyphenols

AKT serine/threonine kinase 1 ; Homo sapiens







37 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34896434 Apple polyphenol phloretin complexed with ruthenium is capable of reprogramming the breast cancer microenvironment through modulation of PI3K/Akt/mTOR/VEGF pathways. 2022 Jan 1 1
2 35321703 Polyphenols in Ilex latifolia Thunb. inhibit human lung cancer cell line A549 by regulation of the PI3K-Akt signaling pathway. 2022 Mar 23 1
3 33641052 New Insights into the Mechanisms of Polyphenol from Plum Fruit Inducing Apoptosis in Human Lung Cancer A549 Cells Via PI3K/AKT/FOXO1 Pathway. 2021 Mar 1
4 33794330 Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways. 2021 Jul 1
5 33805467 Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound. 2021 Mar 29 1
6 33884026 Polyphenols from Broussonetia papyrifera Induce Apoptosis of HepG2 Cells via Inactivation of ERK and AKT Signaling Pathways. 2021 1
7 34044827 The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway. 2021 May 27 1
8 34744708 Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways. 2021 1
9 32135183 Targeting PI3K/Akt/mTOR signaling pathway by polyphenols: Implication for cancer therapy. 2020 Aug 15 3
10 32173528 Cancer cell selective probe by mimicking EGCG. 2020 May 14 1
11 33443209 Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death. 2020 Dec 22 2
12 31059841 Polyphenols in the treatment of autoimmune diseases. 2019 Jul 1
13 31089945 Role of tea polyphenols in delaying hyperglycemia-induced senescence in human glomerular mesangial cells via miR-126/Akt-p53-p21 pathways. 2019 Jun 1
14 31195734 Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features. 2019 Jun 5 4
15 28718669 Fruit Peel Polyphenolic Extract-Induced Apoptosis in Human Breast Cancer Cells Is Associated with ROS Production and Modulation of p38MAPK/Erk1/2 and the Akt Signaling Pathway. 2017 Aug-Sep 2
16 29088809 Anti-inflammatory effects of millet bran derived-bound polyphenols in LPS-induced HT-29 cell via ROS/miR-149/Akt/NF-κB signaling pathway. 2017 Sep 26 1
17 27610044 Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities. 2016 1
18 24251781 Antagonism by bioactive polyphenols against inflammation: a systematic view. 2014 Feb 1
19 25337568 Polyphenols Isolated from Allium cepa L. Induces Apoptosis by Induction of p53 and Suppression of Bcl-2 through Inhibiting PI3K/Akt Signaling Pathway in AGS Human Cancer Cells. 2014 Mar 1
20 23222814 Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells. 2013 Mar 1
21 23963285 Role of endothelial cell membrane transport in red wine polyphenols-induced coronary vasorelaxation: involvement of bilitranslocase. 2013 Oct 1
22 24021570 Polyphenols isolated from Allium cepa L. induces apoptosis by suppressing IAP-1 through inhibiting PI3K/Akt signaling pathways in human leukemic cells. 2013 Dec 1
23 22252293 Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition. 2012 Feb 3 2
24 22715906 Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/β-catenin signaling and FOXO1. 2012 Aug 1
25 23061908 Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. 2012 1
26 21761876 Effect of black currant anthocyanins on the activation of endothelial nitric oxide synthase (eNOS) in vitro in human endothelial cells. 2011 Aug 24 1
27 21776820 Tea polyphenols induce apoptosis through mitochondrial pathway and by inhibiting nuclear factor-kappaB and Akt activation in human cervical cancer cells. 2011 2
28 25214119 Antimetastatic activity of polyphenol-rich extract of Ecklonia cava through the inhibition of the Akt pathway in A549 human lung cancer cells. 2011 Aug 1 1
29 20117080 The EGCg-induced redox-sensitive activation of endothelial nitric oxide synthase and relaxation are critically dependent on hydroxyl moieties. 2010 Feb 26 1
30 20224869 Nutritional improvement of the endothelial control of vascular tone by polyphenols: role of NO and EDHF. 2010 May 2
31 17539658 Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling. 2007 Jun 27 1
32 18059161 Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells. 2007 Dec 1
33 16404708 Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols. 2006 Feb 1
34 15623569 Red wine polyphenol-induced, endothelium-dependent NO-mediated relaxation is due to the redox-sensitive PI3-kinase/Akt-dependent phosphorylation of endothelial NO-synthase in the isolated porcine coronary artery. 2005 Mar 1
35 15249422 Red wine polyphenols induce EDHF-mediated relaxations in porcine coronary arteries through the redox-sensitive activation of the PI3-kinase/Akt pathway. 2004 Aug 1
36 12931129 Suppression of fatty acid synthase in MCF-7 breast cancer cells by tea and tea polyphenols: a possible mechanism for their hypolipidemic effects. 2003 1
37 11756245 Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. 2002 Jan 2