Pub. Date : 2019 Jun 5
PMID : 31195734
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features. | Polyphenols | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | This work aimed to characterize effects of structurally different polyphenols on Akt-phosphorylation (pAkt) in endothelial cells (Ea.hy926) and to describe structure-activity features. | Polyphenols | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | A strong positive and statistically significant correlation between the mean inhibitory effects of the tested polyphenols on both Akt-residues Ser473 and Thr308 (r = 0.9478, p = 0.0003) was determined by immunoblotting. | Polyphenols | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | The suggested molecular mode of action of polyphenols involving Akt-inhibition contributes to understanding their effects on the cellular level. | Polyphenols | AKT serine/threonine kinase 1 | Homo sapiens |