Cyclic AMP

AKT serine/threonine kinase 1 ; Homo sapiens







133 Article(s)
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1 35432308 GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils. 2022 1
2 35474595 CD55 is upregulated by cAMP/PKA/AKT and modulates human decidualization via Src and ERK pathway and decidualization-related genes. 2022 May 2
3 35585611 Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature. 2022 May 18 1
4 32676926 Downregulation of cAMP-Dependent Protein Kinase Inhibitor-b Promotes Preeclampsia by Decreasing Phosphorylated Akt. 2021 Jan 1
5 33433498 Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model. 2021 Aug 1
6 33745150 Genome-wide association study of stage III/IV grade C periodontitis (former aggressive periodontitis) in a Spanish population. 2021 Jul 1
7 34374467 Tetramethylpyrazine induces the release of BDNF from BM-MSCs through activation of the PI3K/AKT/CREB pathway. 2021 Dec 1
8 34867807 Effects of Midazolam on the Development of Adult Leydig Cells From Stem Cells In Vitro. 2021 1
9 31215069 NAD(P)H Quinone Dehydrogenase 1 Ablation Inhibits Activation of the Phosphoinositide 3-Kinase/Akt Serine/Threonine Kinase and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathways and Blocks Metabolic Adaptation in Hepatocellular Carcinoma. 2020 Feb 1
10 31813891 Experimental Study on the Effect of Tibetan Medicine Triphala on the Proliferation and Apoptosis of Pancreatic Islet β Cells through Incretin-cAMP Signaling Pathway. 2020 Feb 1 1
11 32193402 The role of semen and seminal plasma in inducing large-scale genomic changes in the female porcine peri-ovulatory tract. 2020 Mar 19 1
12 32546690 Identification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma. 2020 Jun 16 1
13 33017522 Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma. 2020 Dec 2
14 33082914 Corrigendum to "Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization". 2020 1
15 33187537 DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation. 2020 Nov 13 1
16 30145816 Activation of type 4 metabotropic glutamate receptor promotes cell apoptosis and inhibits proliferation in bladder cancer. 2019 Mar 1
17 30528730 Phosphodiesterase 4B is an effective therapeutic target in colorectal cancer. 2019 Jan 15 2
18 30532074 The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent manner. 2019 Apr 1
19 30794430 M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 via a signaling pathway linking cAMP-PKA and PI3K-Akt. 2019 May 1
20 30867802 Inhibition of phosphodiesterase 4D decreases the malignant properties of DLD-1 colorectal cancer cells by repressing the AKT/mTOR/Myc signaling pathway. 2019 Mar 5
21 31519735 Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes. 2019 Oct 15 1
22 31781320 Integrated Analysis of miRNA-mRNA Interaction Network in Porcine Granulosa Cells Undergoing Oxidative Stress. 2019 1
23 29363568 FKBP51 regulates decidualization through Ser473 dephosphorylation of AKT. 2018 Mar 2
24 29459737 Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. 2018 Feb 19 1
25 29527168 Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats. 2018 2
26 30393564 Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail. 2018 1
27 30568508 Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets. 2018 1
28 27721408 Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance. 2017 Apr 1
29 28232663 cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells. 2017 Feb 24 3
30 28263828 6-Hydroxy-5,7-dimethoxy-flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury. 2017 May 1
31 28912066 The cAMP effectors PKA and Epac activate endothelial NO synthase through PI3K/Akt pathway in human endothelial cells. 2017 Dec 1 1
32 29131834 Plasma microRNA profiling: Exploring better biomarkers for lymphoma surveillance. 2017 1
33 26549736 MiR-150 impairs inflammatory cytokine production by targeting ARRB-2 after blocking CD28/B7 costimulatory pathway. 2016 Apr 2
34 26998266 XB130: A novel adaptor protein in cancer signal transduction. 2016 Mar 1
35 27072494 Exenatide exerts direct protective effects on endothelial cells through the AMPK/Akt/eNOS pathway in a GLP-1 receptor-dependent manner. 2016 Jun 1 1
36 27379018 The Mineralocorticoid Agonist Fludrocortisone Promotes Survival and Proliferation of Adult Hippocampal Progenitors. 2016 1
37 27696687 Phosphatidic acid induces decidualization by stimulating Akt-PP2A binding in human endometrial stromal cells. 2016 Nov 3
38 27765922 G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion. 2016 Oct 25 1
39 25524737 PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells. 2015 Jan 15 2
40 25576220 MicroRNA-124 regulates glucocorticoid sensitivity by targeting phosphodiesterase 4B in diffuse large B cell lymphoma. 2015 Mar 1 2
41 24200882 Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3. 2014 Feb 1
42 24621265 Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells. 2014 Aug 1
43 24654606 PI3Kγ integrates cAMP and Akt signalling of the μ-opioid receptor. 2014 Jul 4
44 24786832 JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway. 2014 Aug 2
45 23380369 Membrane receptor cross talk in steroidogenesis: recent insights and clinical implications. 2013 Jun 1
46 23529183 C2238 atrial natriuretic peptide molecular variant is associated with endothelial damage and dysfunction through natriuretic peptide receptor C signaling. 2013 May 10 1
47 23657011 Reciprocal regulation of PKA and Rac signaling. 2013 May 21 2
48 23836899 Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor α (ERRα). 2013 Aug 30 1
49 24322054 Interplay of PKA and Rac: fine-tuning of Rac localization and signaling. 2013 Oct-Dec 1
50 22173835 Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex. 2012 May 5