Pub. Date : 2019 Jan 15
PMID : 30528730
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, cAMP modulated the activities of AKT and AMPK in a PDE4B-dependent manner, which was associated with a marked decrease in mTOR-Myc signals and oncogenic properties of CRC cells such as anchorage-independent growth and colony formation. | Cyclic AMP | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | We found that the Myc proto-oncogene was a crucial downstream target of the AKT/mTOR and AMPK/mTOR signals that mediated cAMP-induced anti-tumor effect. | Cyclic AMP | AKT serine/threonine kinase 1 | Homo sapiens |