Fatty Acids

ATP citrate lyase ; Homo sapiens







59 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35177584 Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells. 2022 Feb 17 1
2 35436171 ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective. 2022 Jul 2
3 35449157 USP22 regulates lipidome accumulation by stabilizing PPARĪ³ in hepatocellular carcinoma. 2022 Apr 21 3
4 35634242 Targeting lipid metabolism in the treatment of ovarian cancer. 2022 1
5 32448086 Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study. 2021 Jul 3
6 33199826 A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer. 2021 Jan 1
7 34344378 Identification and integrative analysis of ACLY and related gene panels associated with immune microenvironment reveal prognostic significance in hepatocellular carcinoma. 2021 Aug 3 1
8 34491895 ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation. 2021 Sep 7 1
9 34635427 The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis. 2021 Dec 1
10 34718375 Epicatechin gallate prevents the de novo synthesis of fatty acid and the migration of prostate cancer cells. 2021 Dec 8 1
11 31499095 ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: An updated review. 2020 Jan 2
12 31947614 The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis. 2020 Jan 14 2
13 31978345 FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. 2020 Jan 23 1
14 32054087 In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis. 2020 Feb 11 1
15 32670813 Withania somnifera root extract inhibits fatty acid synthesis in prostate cancer cells. 2020 May 2
16 32692565 Cell Metabolomics Reveals Berberine-Inhibited Pancreatic Cancer Cell Viability and Metastasis by Regulating Citrate Metabolism. 2020 Sep 4 2
17 32891058 Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes. 2020 Aug 20 1
18 33134163 m6A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1. 2020 1
19 30586346 Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis. 2019 Feb 1
20 30853332 A role for ATP Citrate Lyase in cell cycle regulation during myeloid differentiation. 2019 May 1
21 31141698 Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. 2019 May 28 1
22 31775252 ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile. 2019 Nov 25 2
23 29432553 Short-term heat stress altered metabolism and insulin signaling in skeletal muscle. 2018 Feb 15 1
24 30176945 Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours. 2018 Sep 3 1
25 30195238 ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism. 2018 Sep 5 1
26 27997879 Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase. 2017 Jan 27 2
27 28059952 ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. 2017 Apr 1
28 28230778 Caffeic Acid Expands Anti-Tumor Effect of Metformin in Human Metastatic Cervical Carcinoma HTB-34 Cells: Implications of AMPK Activation and Impairment of Fatty Acids De Novo Biosynthesis. 2017 Feb 21 2
29 28443474 ATP citrate lyase is increased in human breast cancer, depletion of which promotes apoptosis. 2017 Apr 1
30 28637447 Differential gene expression at different stages of mesocarp development in high- and low-yielding oil palm. 2017 Jun 21 1
31 26477310 Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells. 2016 May 1
32 26784936 Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid. 2016 Feb 11 1
33 27248322 Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism. 2016 Jul 12 3
34 27663902 Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase. 2016 Oct 3
35 27760311 ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch. 2016 Oct 18 1
36 27892457 Amplification of USP13 drives ovarian cancer metabolism. 2016 Nov 28 1
37 25367309 ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway. 2015 Jan 1
38 25962060 Prognostic Value of Malic Enzyme and ATP-Citrate Lyase in Non-Small Cell Lung Cancer of the Young and the Elderly. 2015 2
39 26073398 Adenosine triphosphate citrate lyase: Emerging target in the treatment of dyslipidemia. 2015 May-Jun 1
40 26221340 ATP citrate lyase expression is associated with advanced stage and prognosis in gastric adenocarcinoma. 2015 2
41 24310723 Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells. 2014 Jul 1 8
42 22045812 Identification of a new fatty acid synthesis-transport machinery at the peroxisomal membrane. 2012 Jan 2 1
43 22718913 ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms. 2012 Sep 4
44 22012398 Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. 2011 Oct 19 1
45 20558738 Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography. 2010 Aug 27 1
46 19286649 A novel direct homogeneous assay for ATP citrate lyase. 2009 Oct 1
47 18922930 ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer. 2008 Oct 15 2
48 17476502 Chemistry, physiological properties, and microbial production of hydroxycitric acid. 2007 Jul 1
49 15234082 Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. 2004 Sep 1
50 10777536 Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins. 2000 Apr 28 1