Title : Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis.

Pub. Date : 2019 Feb

PMID : 30586346






1 Functional Relationships(s)
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1 RECENT FINDINGS: The liver-specific activation of bempedoic acid inhibits ACLY, a key enzyme linking glucose catabolism to lipogenesis by catalyzing the formation of acetyl-CoA from mitochondrial-derived citrate for de novo synthesis of fatty acids and cholesterol. Fatty Acids ATP citrate lyase Homo sapiens