Tacrolimus

cytochrome p450 oxidoreductase ; Homo sapiens







27 Article(s)
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1 35213993 Association of P450 Oxidoreductase Gene Polymorphism with Tacrolimus Pharmacokinetics in Renal Transplant Recipients: A Systematic Review and Meta-Analysis. 2022 Jan 22 7
2 35578867 Impact of POR*28 Variant on Tacrolimus Pharmacokinetics in Kidney Transplant Patients with Different CYP3A5 Genotypes. 2022 May 16 1
3 35629245 Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants. 2022 May 19 1
4 32225074 Influence of POR*28 Polymorphisms on CYP3A5*3-Associated Variations in Tacrolimus Blood Levels at an Early Stage after Liver Transplantation. 2020 Mar 26 4
5 32453653 Effects of CYP3A5, ABCB1 and POR*28 polymorphisms on pharmacokinetics of tacrolimus in the early period after renal transplantation. 2020 Dec 3
6 30323313 Impact of single nucleotide polymorphisms on P450 oxidoreductase and peroxisome proliferator-activated receptor alpha on tacrolimus pharmacokinetics in renal transplant recipients. 2019 Feb 1
7 31096684 Impact of CYP3A5, POR, and CYP2C19 Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation. 2019 May 15 3
8 28094348 Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant. 2018 Jan 1
9 29629825 CYP3A pharmacogenetic association with tacrolimus pharmacokinetics differs based on route of drug administration. 2018 Apr 1
10 29878980 Impact of POR and CYP3A5 Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in the Early Post-operative Period Following Kidney Transplantation. 2018 Oct 4
11 30040022 Tacrolimus population pharmacokinetic models according to CYP3A5/CYP3A4/POR genotypes in Chinese Han renal transplant patients. 2018 Aug 1 1
12 28229376 The Pharmacogenetics of Tacrolimus in Corticosteroid-Sparse Pediatric and Adult Kidney Transplant Recipients. 2017 Jun 2
13 26829596 A Lack of Significant Effect of POR*28 Allelic Variant on Tacrolimus Exposure in Kidney Transplant Recipients. 2016 Apr 1
14 27498776 The POR rs1057868-rs2868177 GC-GT diplotype is associated with high tacrolimus concentrations in early post-renal transplant recipients. 2016 Sep 7
15 26067485 Multigene predictors of tacrolimus exposure in kidney transplant recipients. 2015 Jul 3
16 26227094 The genetic polymorphisms of POR*28 and CYP3A5*3 significantly influence the pharmacokinetics of tacrolimus in Chinese renal transplant recipients. 2015 Sep 7
17 24061445 Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients. 2014 Feb 2
18 24089076 P450 oxidoreductase *28 (POR*28) and tacrolimus disposition in pediatric kidney transplant recipients--a pilot study. 2014 Apr 3
19 24249597 The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation. 2014 Feb 1
20 24465960 Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipients. 2014 1
21 24658827 The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. 2014 Jun 1
22 24739669 CYP3A5*3 and POR*28 genetic variants influence the required dose of tacrolimus in heart transplant recipients. 2014 Dec 2
23 24921414 Impact of PPARA and POR polymorphisms on tacrolimus pharmacokinetics and new-onset diabetes in kidney transplant recipients. 2014 Aug 2
24 25322286 Combined effects of CYP3A5*1, POR*28, and CYP3A4*22 single nucleotide polymorphisms on early concentration-controlled tacrolimus exposure in de-novo renal recipients. 2014 Dec 3
25 23097010 Effect of the P450 oxidoreductase 28 polymorphism on the pharmacokinetics of tacrolimus in Chinese healthy male volunteers. 2013 Apr 3
26 24113216 Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus. 2013 Dec 2
27 21770725 The P450 oxidoreductase *28 SNP is associated with low initial tacrolimus exposure and increased dose requirements in CYP3A5-expressing renal recipients. 2011 Sep 3