Pub. Date : 2017 Jun
PMID : 28229376
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Variants in the genes PPARA, POR and CYP3A4 have recently been shown to influence tacrolimus metabolism. | Tacrolimus | cytochrome p450 oxidoreductase | Homo sapiens |
| 2 | In the present study, we investigated a potential association between CYP3A5*3, PPARA c.209-1003G>A, POR*28 and CYP3A4*22 and dose-adjusted tacrolimus trough concentrations in a primarily corticosteroid-free (>85%) population of Danish pediatric and adult kidney transplant recipients. | Tacrolimus | cytochrome p450 oxidoreductase | Homo sapiens |