Benzo(a)pyrene

transformation related protein 53, pseudogene ; Mus musculus







30 Article(s)
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1 28681665 Stimulatory effects of curcumin and quercetin on posttranslational modifications of p53 during lung carcinogenesis. 2018 Jun 2
2 26679980 Subchronic exposure of benzo(a)pyrene interferes with the expression of Bcl-2, Ki-67, C-myc and p53, Bax, Caspase-3 in sub-regions of cerebral cortex and hippocampus. 2016 Feb-Mar 1
3 26709117 Disturbance of Bcl-2, Bax, Caspase-3, Ki-67 and C-myc expression in acute and subchronic exposure to benzo(a)pyrene in cervix. 2016 Mar 1
4 27608907 Study to elucidate molecular mechanism behind zinc chemo-preventive role during lung carcinogenesis. 2016 Aug 3
5 24412381 Benzo[a]pyrene increases DNA double strand break repair in vitro and in vivo: a possible mechanism for benzo[a]pyrene-induced toxicity. 2014 Jan 15 1
6 24705375 Study to evaluate molecular mechanics behind synergistic chemo-preventive effects of curcumin and resveratrol during lung carcinogenesis. 2014 3
7 22828138 Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days. 2012 Nov 4
8 21715664 Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene. 2011 Sep 1
9 21745588 A common carcinogen benzo[a]pyrene causes p53 overexpression in mouse cervix via DNA damage. 2011 Sep 18 3
10 20103645 Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors. 2010 Feb 1 1
11 18248503 p53 gene mutations in SKH-1 mouse tumors differentially induced by UVB and combined subcarcinogenic benzo[a]pyrene and UVA. 2008 Mar-Apr 2
12 19105532 Immunohistochemical study of fibrosis and adenocarcinoma in dominant-negative p53 transgenic mice exposed to chrysotile asbestos and benzo(a)pyrene. 2008 2
13 17433523 Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation. 2007 Jun 3 1
14 16244358 Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase. 2006 Mar 2
15 15641149 Inhibitory effects of polysaccharides isolated from Phellinus gilvus on benzo(a)pyrene-induced forestomach carcinogenesis in mice. 2005 Jan 28 1
16 16050805 Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ. 2005 1
17 16254190 Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53. 2005 Oct 1
18 16297369 p38 MAP kinase regulates benzo(a)pyrene-induced apoptosis through the regulation of p53 activation. 2005 Dec 15 1
19 15125997 Benzo(a)pyrene-induced apoptotic death of mouse hepatoma Hepa1c1c7 cells via activation of intrinsic caspase cascade and mitochondrial dysfunction. 2004 Jun 1 3
20 15449320 Role of cell signalling involved in induction of apoptosis by benzo[a]pyrene and cyclopenta[c,d]pyrene in Hepa1c1c7 cells. 2004 Dec 15 4
21 12733653 The combination of benzo[a]pyrene and ultraviolet A causes an in vivo time-related accumulation of DNA damage in mouse skin. 2003 Apr 1
22 12151310 Lung-specific expression of dominant-negative mutant p53 in transgenic mice increases spontaneous and benzo(a)pyrene-induced lung cancer. 2002 Aug 1
23 11096091 Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells. 2001 Feb 16 3
24 11195457 Use of p53 transgenic mice in the development of cancer models for multiple purposes. 2000 Dec 2
25 10469621 Thapsigargin has similar effect on p53 protein response to benzo[a]pyrene-DNA adducts as TPA in mouse skin. 1999 Sep 3
26 9006915 A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. 1997 Jan 31 1
27 8681459 TPA decreases the p53 response to benzo[a]pyrene-DNA adducts in vivo in mouse skin. 1996 Jun 2
28 9051119 Cell proliferation and nuclear abnormalities are increased and apoptosis is decreased in the epidermis of the p53 null mouse after topical application of benzo[a]pyrene. 1996 Oct 1
29 7663513 A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. 1995 Jun 1
30 8055640 Murine squamous cell carcinoma cell lines produced by a complete carcinogenesis protocol with benzo[a]pyrene exhibit characteristic p53 mutations and the absence of H-ras and cyl 1/cyclin D1 abnormalities. 1994 Aug 1