Oligonucleotides

intercellular adhesion molecule 1 ; Homo sapiens







74 Article(s)
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1 29207381 Alicaforsen, an Antisense Inhibitor of Intercellular Adhesion Molecule-1, in the Treatment for Left-Sided Ulcerative Colitis and Ulcerative Proctitis. 2018 1
2 29757363 Targeting Endothelial Ligands: ICAM-1/alicaforsen, MAdCAM-1. 2018 Aug 22 2
3 30137311 Past, Present and Future of Therapeutic Interventions Targeting Leukocyte Trafficking in Inflammatory Bowel Disease. 2018 Aug 22 1
4 29067882 Alicaforsen in the treatment of pouchitis. 2017 Nov 1
5 26966529 Alicaforsen, an antisense inhibitor of ICAM-1, as treatment for chronic refractory pouchitis after proctocolectomy: A case series. 2016 Feb 2
6 23473419 Silver nanoscale antisense drug delivery system for photoactivated gene silencing. 2013 Apr 23 2
7 23555914 HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy. 2013 1
8 22128256 Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-α and IFNγ-stimulated Primary Cultured Astrocytes. 2011 Oct 1
9 20083573 HIV gp120 induces endothelial dysfunction in tumour necrosis factor-alpha-activated porcine and human endothelial cells. 2010 Jul 15 1
10 17979170 2'-O-Lysylaminohexyl oligonucleotides: modifications for antisense and siRNA. 2008 Jan 1
11 18322230 Cross-talk between ICAM-1 and granulocyte-macrophage colony-stimulating factor receptor signaling modulates eosinophil survival and activation. 2008 Mar 15 1
12 16669955 Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial. 2006 May 15 1
13 16669956 A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis. 2006 May 15 1
14 16764540 Plasma protein binding of an antisense oligonucleotide targeting human ICAM-1 (ISIS 2302). 2006 Summer 1
15 16937430 Novel strategies for the treatment of inflammatory bowel disease: Selective inhibition of cytokines and adhesion molecules. 2006 Aug 7 2
16 15489375 VCAM-1 upregulation via PKCdelta-p38 kinase-linked cascade mediates the TNF-alpha-induced leukocyte adhesion and emigration in the lung airway epithelium. 2005 Feb 1
17 15591117 Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. 2005 Apr 1 1
18 15790759 Transcriptional regulation of inflammatory mediators secreted by human colonic circular smooth muscle cells. 2005 Aug 3
19 15860735 Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium. 2005 Jul 1
20 16158332 Intercellular adhesion molecule-1 (ICAM-1) in ulcerative colitis: presence, visualization, and significance. 2005 Aug 2
21 16197343 Alicaforsen therapy in inflammatory bowel disease. 2005 Oct 2
22 14688373 Intercellular adhesion molecule-1 mediates cellular cross-talk between parenchymal and immune cells after lipopolysaccharide neutralization. 2004 Jan 1 1
23 14695770 Cooperative inhibitory effects of antisense oligonucleotide of cell adhesion molecules and cimetidine on cancer cell adhesion. 2004 Jan 1
24 15063042 On the biological activity of anti-ICAM-1 oligonucleotides complexed to non-viral carriers. 2004 Apr 16 2
25 15480988 TNFalpha suppresses human colonic circular smooth muscle cell contractility by SP1- and NF-kappaB-mediated induction of ICAM-1. 2004 Oct 1
26 15617021 Effects of human and murine antisense oligonucleotide inhibitors of ICAM-1 on reproductive performance, fetal development, and post-natal development in mice. 2004 Dec 1
27 15617022 Effects of an antisense oligonucleotide inhibitor of human ICAM-1 on fetal development in rabbits. 2004 Dec 1
28 12826223 Prevention of renal ischemic reperfusion injury using FTY 720 and ICAM-1 antisense oligonucleotides. 2003 Jun 2
29 14527564 Antisense phosphorothioate oligodeoxyribonucleotide targeted against ICAM-1: synthetic and biological characterization of a process-related impurity formed during oligonucleotide synthesis. 2003 Oct 15 1
30 12074367 Antisense-mediated inhibition of ICAM-1 expression: a therapeutic strategy against inflammation of human periodontal tissue. 2002 Apr 1
31 12077088 Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease. 2002 Jul 2
32 12269969 Dose ranging pharmacokinetic trial of high-dose alicaforsen (intercellular adhesion molecule-1 antisense oligodeoxynucleotide) (ISIS 2302) in active Crohn's disease. 2002 Oct 1
33 11181922 Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats. 2001 Mar 1
34 11229813 Sialyl Lewis(x)-liposomes as vehicles for site-directed, E-selectin-mediated drug transfer into activated endothelial cells. 2001 Jan 1
35 11233988 Mapping of RNA accessible sites by extension of random oligonucleotide libraries with reverse transcriptase. 2001 Feb 1
36 11266874 Development of an oral formulation for ICAM-1 antisense oligonucleotides. 2001 Feb-Mar 1
37 11267100 Methoxyethyl modification of phosphorothioate ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury. 2001 Feb-Mar 1
38 11313303 Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease. 2001 May 1
39 11532196 Different effects of antisense RelA p65 and NF-kappaB1 p50 oligonucleotides on the nuclear factor-kappaB mediated expression of ICAM-1 in human coronary endothelial and smooth muscle cells. 2001 3
40 11577588 [Antibodies and immunomodulation]. 2001 Sep 1 1
41 11750578 Phosphorothioate/methoxyethyl-modified ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury. 2001 Nov-Dec 1
42 10623843 Mechanism and function of a newly identified CpG DNA motif in human primary B cells. 2000 Jan 15 1
43 10630964 The antisense oligonucleotide ISIS 2922 prevents cytomegalovirus-induced upregulation of IL-8 and ICAM-1 in cultured human fibroblasts. 2000 Mar 1
44 10706053 Attenuation of cytomegalovirus-induced endothelial intercellular adhesion molecule-1 mRNA/protein expression and T lymphocyte adhesion by a 2'-O-methoxyethyl antisense oligonucleotide. 2000 Feb 15 7
45 11069617 Intercellular adhesion molecule-1 suppression in skin by topical delivery of anti-sense oligonucleotides. 2000 Nov 1
46 10037819 Oligonucleotide-europium complex conjugate designed to cleave the 5' cap structure of the ICAM-1 transcript potentiates antisense activity in cells. 1999 Mar 15 3
47 10378368 [ICAM-1 antisense therapy: a new treatment concept on Crohn disease? Placebo controlled study of ICAM-1 antisense oligonucleotide therapy in Crohn disease]. 1999 Apr 1
48 10430938 CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. 1999 Aug 3 1
49 10438903 Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells. 1999 Aug 15 1
50 10453007 Human endothelial cells augment early CD40 ligand expression in activated CD4+ T cells through LFA-3-mediated stabilization of mRNA. 1999 Sep 1 1