Title : 2'-O-Lysylaminohexyl oligonucleotides: modifications for antisense and siRNA.

Pub. Date : 2008 Jan

PMID : 17979170






1 Functional Relationships(s)
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1 Incorporation of up to three modifications into functional antisense and siRNA oligonucleotides targeted at ICAM-1 showed that the gene-silencing activity was higher with an increasing number of lysylaminohexyl nucleotides. Oligonucleotides intercellular adhesion molecule 1 Homo sapiens