| 1 |
34773126 | Investigations on detoxification mechanisms of novel para-phenylenediamine analogues through N-acetyltransferase 1 (NAT-1). | 2022 Jan |
1 |
| 2 |
35273499 | 560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment. | 2022 |
2 |
| 3 |
35353990 | Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells. | 2022 May 1 |
1 |
| 4 |
31910058 | Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV. | 2020 Dec |
1 |
| 5 |
32555504 | CRISPR/Cas9 knockout of human arylamine N-acetyltransferase 1 in MDA-MB-231 breast cancer cells suggests a role in cellular metabolism. | 2020 Jun 17 |
1 |
| 6 |
31358821 | Population variability of rhesus macaque (Macaca mulatta) NAT1 gene for arylamine N-acetyltransferase 1: Functional effects and comparison with human. | 2019 Jul 29 |
2 |
| 7 |
29180287 | Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation. | 2018 Feb |
2 |
| 8 |
29964355 | Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity. | 2018 Nov |
1 |
| 9 |
26168740 | Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance. | 2015 Jul 14 |
1 |
| 10 |
24319536 | CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population. | 2013 |
2 |
| 11 |
21837760 | NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl. | 2012 Aug |
1 |
| 12 |
22010219 | Phenotype of the most common "slow acetylator" arylamine N-acetyltransferase 1 genetic variant (NAT1*14B) is substrate-dependent. | 2012 Jan |
3 |
| 13 |
22114069 | Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct. | 2012 Feb |
4 |
| 14 |
21347396 | RNAi-mediated knock-down of arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition. | 2011 Feb 9 |
2 |
| 15 |
19842618 | Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines. | 2009 Dec |
4 |
| 16 |
18259988 | Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1. | 2008 |
1 |
| 17 |
18288399 | Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer. | 2008 Mar |
1 |
| 18 |
18759501 | Human arylamine N-acetyltransferase 1: in vitro and intracellular inactivation by nitrosoarene metabolites of toxic and carcinogenic arylamines. | 2008 Oct |
1 |
| 19 |
16397907 | N-acetyltransferase 2 polymorphism in patients with diabetes mellitus. | 2007 Jul-Aug |
1 |
| 20 |
17392017 | Arylamine N-acetyltransferase I. | 2007 |
1 |
| 21 |
17537267 | Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma. | 2007 May 30 |
1 |
| 22 |
17672512 | Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2. | 2007 Sep |
2 |
| 23 |
16857211 | Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation. | 2006 Aug 18 |
1 |
| 24 |
14705222 | N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus. | 2004 Jan |
1 |
| 25 |
15142281 | NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant. | 2004 Mar 17 |
1 |
| 26 |
15320760 | Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: role of genetic and non genetic factors. | 2004 |
1 |
| 27 |
15450435 | Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system. | 2004 Oct 4 |
2 |
| 28 |
12618593 | Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster. | 2003 Mar |
3 |
| 29 |
12754290 | Skeletal muscles express the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase. | 2003 Jun |
1 |
| 30 |
12088197 | Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition. | 2002 |
2 |
| 31 |
12376500 | XPD codon 751 polymorphism, metabolism genes, smoking, and bladder cancer risk. | 2002 Oct |
1 |
| 32 |
11207033 | Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects. | 2001 Feb |
2 |
| 33 |
14564055 | Association of arylamine N-acetyltransferase (NAT1 and NAT2) genotypes with urinary bladder cancer risk. | 2001 |
1 |
| 34 |
10692486 | Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. | 2000 Mar |
2 |
| 35 |
10746928 | Localization of N-acetyltransferases NAT1 and NAT2 in human tissues. | 2000 Mar |
1 |
| 36 |
10794727 | Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2. | 2000 May 15 |
1 |
| 37 |
10971207 | Pharmacogenetics of the human arylamine N-acetyltransferases. | 2000 Sep |
2 |
| 38 |
11108798 | Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid. | 2000 Dec 15 |
2 |
| 39 |
9511183 | Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations. | 1998 Feb |
2 |
| 40 |
9572394 | Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter. | 1998 |
1 |
| 41 |
9577349 | Expression of arylamine N-acetyltransferase in human intestine. | 1998 Mar |
1 |
| 42 |
8960058 | A fragment consisting of the first 204 amino-terminal amino acids of human arylamine N-acetyltransferase one (NAT1) and the first transacetylation step of catalysis. | 1997 Jan 10 |
2 |
| 43 |
9173883 | Study of the role of the highly conserved residues Arg9 and Arg64 in the catalytic function of human N-acetyltransferases NAT1 and NAT2 by site-directed mutagenesis. | 1997 Apr 1 |
3 |
| 44 |
9202739 | Human acetyltransferase polymorphisms. | 1997 May 12 |
1 |
| 45 |
9321764 | A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid. | 1997 Sep |
1 |
| 46 |
7920698 | Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity. | 1994 Jun |
1 |
| 47 |
8353847 | Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. | 1993 Aug |
5 |
| 48 |
1423830 | The role of the human acetylation polymorphism in the metabolic activation of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). | 1992 Oct |
1 |
| 49 |
1996083 | Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. | 1991 Feb |
1 |