Pub. Date : 2003 Mar
PMID : 12618593
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | N-acetylation and O-acetylation, catalysed by N-acetyltransferase 1 (NAT1) and 2 (NAT2), activate and/or deactivate arylamines to electrophilic intermediates that bind DNA and initiate tumours in target organs. | aniline | N-acetyltransferase 1 | Homo sapiens |
| 2 | N-acetylation and O-acetylation, catalysed by N-acetyltransferase 1 (NAT1) and 2 (NAT2), activate and/or deactivate arylamines to electrophilic intermediates that bind DNA and initiate tumours in target organs. | aniline | N-acetyltransferase 1 | Homo sapiens |
| 3 | NAT1 and NAT2 in liver and prostate catalysed -acetylation of the arylamines above and O-acetylation of N-hydroxy derivatives of 2-aminofluorene, 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | aniline | N-acetyltransferase 1 | Homo sapiens |