Pub. Date : 2001 Feb
PMID : 11207033
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | The goals of the present study were (i) to assay for the presence of the arylamine acetyltransferases NAT1 and NAT2, and of the cytochrome P450 isoform CYP1A2, in human bladder epithelium; and (ii) to determine whether the activities of these arylamine biotransforming enzymes differ between bladder cancer patients and control subjects. | aniline | N-acetyltransferase 1 | Homo sapiens | ||
| 2 | Our results suggest that although expression of particular arylamine biotransforming enzymes within the bladder tissue could play a significant role in locally bioactivating arylamine procarcinogens in theory, interindividual variations in CYP1A2, NAT1 and NAT2 activities do not significantly differ between bladder cancer patients and control subjects when potential arylamine exposures are controlled for | aniline | N-acetyltransferase 1 | Homo sapiens | ||